research 2,5-Diazabicyclo[2.2.1]heptane in medicinal chemistry: a treasure trove of therapeutic opportunities
2,5-DBH shows promise for improving drugs in cancer, brain disorders, and infections.
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research Innovative sequence of docetaxel–gemcitabine based on preclinical data in the treatment of advanced non small cell lung cancer: a phase I study
The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.
research Profibrotic Molecules Are Reduced in CRISPR-Edited Emery–Dreifuss Muscular Dystrophy Fibroblasts
CRISPR gene editing reduces harmful molecules in cells from Emery–Dreifuss Muscular Dystrophy patients.
research Synthesis and characterization of inclusion complex of the vasodilator drug minoxidil with β-cyclodextrin
Minoxidil mixed with β-cyclodextrin improves solubility and gradual release.
research Efecto del extracto hidroetanólico de semillas de Coffea arabica L. sobre la hiperplasia prostática inducida en Mus musculus var. swiss orquiectomizados
Low doses of Coffea arabica seed extract prevent prostate growth and lower uric acid and PSA levels.
research Novel micelle formulations to increase cutaneous bioavailability of azole antifungals
New micelle solutions greatly improve skin delivery of certain antifungal drugs.
research Young coconut juice can accelerate the healing process of cutaneous wounds
Young coconut juice speeds up wound healing.
research Sex hormones and related compounds, including hormonal contraceptives
Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.
research THERAPEUTIC HOTLINE: Effectiveness of the association of cetirizine and topical steroids in lichen planus pilaris - an open-label clinical trial
Combining cetirizine and topical steroids can effectively manage severe lichen planus pilaris.
research Hypersensitivity Reactions to Anticoagulant Drugs
Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.
research Solvent-Containing Closure Material Can Be Used to Prevent Follicular Penetration of Caffeine and Fluorescein Sodium Salt on Porcine Ear Skin
Standard nail varnish effectively prevents follicular penetration of certain substances.
research Hollow-adjustable polymer microneedles for prolonged hypoglycemic effect on diabetic rats
research Effect of ethanol Adiantum capillus-veneris extract in experimental models of anxiety and depression
Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.
research Analisis Potensi Hasil Fraksinasi Dari Ekstrak Etanol Daun Pacing (Costus spicatus (Jacq.) Sw.) sebagai Bahan Baku Obat Herbal terhadap Uji Aktivitas Pertumbuhan Rambut Kelinci
Pacing leaf extracts can promote hair growth in rabbits, but minoxidil works better.
research Determination of the Effects of Eruca sativa Oil, Sodium Carbonate, Lavender Oil and Aloe vera Oil on Lipid Profile and Breast Tumour Markers in Breast Cancer-induced Doxorubicin Treated Female Albino Rats
Eruca sativa oil, Aloe vera oil, and sodium carbonate may help improve cholesterol and tumor markers in breast cancer treatment.
research Controlled Release of the α-Tocopherol-Derived Metabolite α-13′-Carboxychromanol from Bacterial Nanocellulose Wound Cover Improves Wound Healing
Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.
research Compatibility Studies of Minoxidil with Different Excipients by Using DSC, TGA and FTIR
Minoxidil is compatible with some excipients but not with others, affecting formulation choices.
research FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
![Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Untested Compounds](/images/research/6712367a-949f-47c7-a756-2bfe6316fc69/small/15331.jpg)
research Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Nontested Compounds
The research found a link between certain molecular features and the biological activity of BC3, which can help identify or create new active compounds.
research The Promoting Effect of Rumex japonicas Houttuyn ethanol extract on Hair Growth
Rumex japonicas Houttuyn ethanol extract helps increase hair growth and protect against hair damage.
research Role of GABA-active neurosteroids in the efficacy of metyrapone against cocaine addiction
Neurosteroids may help metyrapone reduce cocaine addiction.
research Allergic Dermatitis in Pêga Breed Donkeys (Equus asinus) Caused by Culicoides Bites in the Amazon Biome, Pará, Brazil
Copaiba oil and multivitamin emulsion can effectively treat allergic dermatitis in donkeys caused by Culicoides bites.
research Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy.
Valproic acid is an effective and safe first-choice treatment for many types of seizures.
research Preparation of finasteride by selective dehydrogenation using IBX
The method produces finasteride with a 92% yield.
research Doxetaxel: new indication. Prostate cancer: a few more weeks.
Docetaxel slightly extends prostate cancer survival but has significant side effects and high cost.
research Study preparation of Finasteride Dispersible Tablets and its vitro dissolution
The tablets are easy to make, look good, work well, and are ready for mass production.
research Case Report: Analytically Confirmed Severe Albenzadole Overdose Presenting with Alopecia and Pancytopenia
Overdosing on veterinary albendazole can cause severe health issues like hair loss and low blood cell count.
research Counterfeit drugs and pharmaceutical preparations seized from the black market among bodybuilders
Many black market drugs for bodybuilders are fake and mislabeled.
research Post-natal development of rats` offspring treated with the ethanol extract of Neem leaves (Azadirachta indica A. Juss) during pregnancy and lactation
Neem extract is safe for pregnant or lactating rats at tested doses.
research Treatment of Hirsutism, Acne and Alopecia with Cyproterone Acetate
Cyproterone acetate was effective in treating acne, hirsutism, and alopecia with few side effects.