research Building Epithelial Tissues from Skin Stem Cells
Skin stem cells help maintain skin health, grow hair, and heal wounds.
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research Endogenous retinoids in the hair follicle and sebaceous gland
Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
research Isolation of Stem Cells and Progenitors from Mouse Epidermis
A method was developed to isolate and study hair follicle stem cells from mouse skin.
research Engineering the niche for hair regeneration — A critical review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research Advances in molecular pathogenesis of hidradenitis suppurativa: Dysregulated keratins and ECM signaling
Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
research A Hairy Cituation – PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Co-expression of PADI isoforms during progenitor differentiation enables functional diversity
Different PADI isoforms help cells develop diverse functions.
research Fullerene nanoparticle in dermatological and cosmetic applications
Fullerenes show potential in skin care but need more safety research.
research Androgens induce sebaceous differentiation in sebocyte cells expressing a stable functional androgen receptor
Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
research Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway
miR-181a-5p helps hair growth by activating a specific signaling pathway.
research Highly Efficient Neural Differentiation of CD34-Positive Hair-Follicle-Associated Pluripotent Stem Cells Induced by Retinoic Acid and Serum-Free Medium
Hair follicle stem cells can become nerve cells using specific treatments.
research Deletion of vitamin D receptor with calcium sensing receptor in keratinocytes promotes epidermal tumorigenesis by limiting dna repair and oxidative stress response genes
Deleting vitamin D and calcium receptors in skin cells increases skin cancer risk by reducing DNA repair and stress response.
research The Extract of Periplaneta americana (L.) Promotes Hair Regrowth in Mice with Alopecia by Regulating the FOXO/PI3K/AKT Signaling Pathway and Skin Microbiota
Periplaneta americana extract helps hair regrowth in mice with alopecia.
research Secretome of Hypoxic Mesenchymal Stem Cells Improves Fluconazole-Induced Alopecia in Rats via Immunoregulatory Modulation of IL-15 and IFN-γ
A gel from stem cells can reduce baldness caused by fluconazole in rats.
research Lethal dose Examination and Effect of Different Part Extracts of Ageratum conyzoides L on Hematology and Serum Electrolytes of Streptozotocin Induce Diabetic Rats
Ageratum conyzoides may lower blood sugar and improve blood lipid levels in diabetic rats.
research The effect of minoxidil on endothelial cells
Minoxidil temporarily stops endothelial cell growth without major changes in protein production or movement.
research Fat grafts enriched with ex‐vivo expanded adipose stem cells improve hyperpigmentation of face
Stem cell-enriched fat grafts improve facial hyperpigmentation better than conventional grafts.
research Ferreting out stem cells from their niches
New methods have greatly improved our understanding of stem cell behavior and roles in the body.
research Disruption of Smad4 in Mouse Epidermis Leads to Depletion of Follicle Stem Cells
Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
research Cellular senescence in tissue repair: every cloud has a silver lining
Cell aging can be both good and bad for tissue repair.
research CCN2 modulates hair follicle cycling in mice
The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.
research The mechanisms and functions of interorganelle interactions
Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Watching hair grow
Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.
research BRCA2 in abscission
The tumor suppressor BRCA2 helps in cell division by bringing key proteins to the area where cells split.
research Basal Cell Carcinoma, Hedgehog Signaling, and Targeted Therapeutics: The Long and Winding Road
New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.
research Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development
Dermal EZH2 controls skin cell development and hair growth in mice.
research VEGF upregulates VEGF receptor-2 on human outer root sheath cells and stimulates proliferation through ERK pathway
VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
research Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-II
The mesenchymal stem cell secretome may effectively treat various diseases as an alternative to traditional stem cell therapies.
research 687 BMP signaling in the hair follicle stem cell niche regulates hair growth and skin pigmentation
BMP signaling controls hair growth and skin color.