research Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress
Caloric stress and differentiation increase IRES translation, affecting stem cell function and potential therapies.
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660-690 / 1000+ resultsresearch Scalp Microbiome Composition in Young Women: Associations with Scalp Type, Sensitivity, and Lifestyle Factors
Scalp microbiome in young women is mainly affected by sensitivity, sebum, and lifestyle.
research Embryologic layers in dermatology: Developmental checkpoint disorders, diagnostic insight, and regenerative futures
Understanding embryologic layers improves skin disorder diagnosis and supports developing targeted therapies.
research Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation
RANKL causes lymph nodes to grow by making certain cells multiply.
research Advances in single-cell transcriptomics in animal research
Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.
research rPanglaoDB: an R package to download and merge labeled single-cell RNA-seq data from the PanglaoDB database
rPanglaoDB helps study rare cell types by merging RNA data, showing fibrocytes aid in healing.
research How different is human hair? A critical appraisal of the reported differences in global hair fibre characteristics and properties towards defining a more relevant framework for hair type classification
Human hair varies widely and should be classified by curl type rather than race.
research Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging
Hair follicle stem cells change states with age, affecting hair growth and aging.
research Deep phenotyping of skin tissue remodeling in patients with systemic sclerosis treated with CD19-CAR T cells
CD19-CAR T cell therapy may help regenerate skin in systemic sclerosis.
research Ancestral Diversity of Skin Reaches Single-Cell Resolution
Ancestry affects skin healing, with non-Hispanic Black patients showing more healing-related fibroblasts than White patients.
research TYK2 Inhibition with Deucravacitinib Improves Clinical Outcomes and Resolves Interferon-Driven Inflammation in Lichen Planopilaris
Deucravacitinib improves symptoms and reduces inflammation in Lichen Planopilaris.
research CXCL12 Drives Reversible Fibroimmune Remodeling in Androgenetic Alopecia Revealed by Single-Cell RNA Sequencing
Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
research SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation
SPT6 prevents excessive skin inflammation by blocking a feedback loop.
research Aligning Stem Cell Models and Postmortem Studies to Query Striatal Neurodevelopment in Schizophrenia
Schizophrenia risk genes may affect early brain development, contributing to the disease.
research Type 2 innate immunity regulates hair follicle homeostasis to control Demodex pathosymbionts
A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.
research Comparative Proteomics Indicates That Biosynthesis of Pectic Precursors Is Important for Cotton Fiber and Arabidopsis Root Hair Elongation
Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.
research Epidermal stem cells and skin tissue engineering in hair follicle regeneration
Hair follicle regeneration needs special conditions and young cells.
research Stem Cell-Enriched Treatments in Aesthetic Medicine: A Comprehensive Scientific Literature Review of Current Applications, Mechanisms, Outcomes, and Future Perspectives
Stem cell treatments show promise for improving skin and hair, but need more research and standardization.
research Mechanisms regulating skin immunity and inflammation
The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
research Alopecia Areata
Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
research The Rotterdam Study: 2018 update on objectives, design and main results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.
research Penetration Profile of Microspheres in Follicular Targeting of Terminal Hair Follicles
Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack
Hair follicles prevent NK cell attacks to avoid hair loss.
research MELATONIN
Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
research Gender-linked differences in human skin
Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
research Probing the Effects of Stress Mediators on the Human Hair Follicle
Stress-related substance P may lead to hair loss and negatively affect hair growth.
research The role of tight junctions in skin barrier function and dermal absorption
Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
research Biocompatible nanoparticles and vesicular systems in transdermal drug delivery for various skin diseases
Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
research Experimental Induction of Alopecia Areata-Like Hair Loss in C3H/HeJ Mice Using Full-Thickness Skin Grafts
Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.