October 2023 in “Annales Academiae Medicae Silesiensis” Saw palmetto extracts might help treat male hair loss and need more research.
414 citations
,
August 2005 in “Nature” Activating TERT in mice skin boosts hair growth by waking up hair follicle stem cells.
148 citations
,
May 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice without the vitamin D receptor are more prone to UV-induced skin tumors.
April 2018 in “Journal of Investigative Dermatology” Blocking a specific immune cell signal can trigger hair growth.
171 citations
,
June 2004 in “Journal of Investigative Dermatology” GLI2 activates GLI1, promoting skin tumor growth and hair development.
3 citations
,
January 2021 in “Oxidative Medicine and Cellular Longevity” Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
132 citations
,
August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
44 citations
,
June 2017 in “The EMBO Journal” LPA3 signaling in the uterus is crucial for placental formation and fetal development.
3 citations
,
May 2022 in “Experimental Dermatology” Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
January 2026 in “Scientific Reports” PCOS involves immune and genetic factors, with key roles for T cells and specific genes.
Hair growth is maintained by specific cell signals.
June 2024 in “Regenerative Therapy” Exosomes from stem cells may help rejuvenate skin and regrow hair, but more research is needed.
23 citations
,
February 2015 in “The American journal of pathology” Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.
7 citations
,
March 2017 in “Experimental and Therapeutic Medicine” Hair follicle cells can help keep embryonic stem cells undifferentiated.
4 citations
,
December 2015 in “Journal of Medicinal Plants Research” A plant mixture extract helped grow hair by boosting cell growth and growth factors while blocking a hair loss-related enzyme.
2 citations
,
June 2016 in “International journal of experimental pathology” Human skin has less GDNF and its receptor with age.
1 citations
,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
March 2026 in “Adipocyte” Spt4 and Spt6 are essential for fat cell development.
November 2023 in “Periodontology 2000” Injectable platelet-rich fibrin has improved healing and regeneration in various medical fields and can be more effective than previous treatments.
September 2023 in “JPRAS Open” Botulinum Toxin A may help with hair growth and has some side effects; more research is needed.
January 2023 in “Open veterinary journal” Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.
September 2016 in “Journal of dermatological science” Collagen XVII is crucial for skin cell growth and nail health.
2 citations
,
January 2023 in “Redox Report” Estradiol may protect ear cells from hearing loss caused by a chemotherapy drug by activating a protective pathway.
93 citations
,
June 2011 in “Journal of Neuroscience” p63 is essential for activating and differentiating stem cells in the nose's olfactory tissue.
27 citations
,
May 2017 in “Marine Drugs” Undariopsis peterseniana extract helps hair grow by activating certain cell growth pathways and could be a new treatment for hair loss.
24 citations
,
July 2018 in “Stem cells” Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.
7 citations
,
January 2019 in “Annals of dermatology/Annals of Dermatology” Synthetic ceramides may help hair growth by boosting cell growth in hair follicles.
4 citations
,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
96 citations
,
October 2000 in “The FASEB Journal” The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.
86 citations
,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.