research 875 Exploring the role of microRNAs in alopecia areata
Certain microRNAs may protect against hair loss in alopecia areata and could be potential treatment targets.
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research 838 Histologic and immunohistochemical evaluation of Lichen Planopilaris and correlation with clinical disease severity
The study found a link between the severity of Lichen Planopilaris seen by doctors and the details seen under a microscope, and created a new way to measure this severity.
research Spatial Gene Profiling in the Ischemic Heart
A new technology showed that the SOX9 gene might control heart scar formation after injury, suggesting new treatment possibilities.
research 1336 The de novo DNA methyltransferase DNMT3A is required for epidermal homeostasis
DNMT3A is crucial for healthy skin and hair growth.
research 1339 Mature adipocytes inhibit the antimicrobial function of dermal adipogenic stem cells: An explanation for impaired cutaneous defense in obesity
Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
research APCDD1 is a novel Wnt inhibitor mutated in hereditary hypotrichosis simplex
A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
research Understanding the functional contribution of dermal stem cells to hair follicle regeneration and skin wound healing
Dermal stem cells help regenerate hair follicles and heal skin wounds.
research Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil
Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.
research Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation
Msx2 and Foxn1 are both crucial for hair growth and health.
research Localisation of members of the notch system and the differentiation of vibrissa hair follicles: Receptors, ligands, and fringe modulators
Notch-related genes play a key role in the development and cycling of hair follicles.
research Wnt target gene Ascl4 is dispensable for skin appendage development
The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
research Dermal EZH2 simultaneously orchestrates Wnt/β-catenin signaling dependent dermal differentiation and retinoic acid signaling dependent epidermal proliferation during murine skin development
Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
research EZH1 and EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair
EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility
Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
research Turing patterns in development: what about the horse part?
Turing patterns are now recognized as important in developmental biology.
research Diversification and Specialization of Touch Receptors in Skin
Skin has specialized touch receptors that can tell different sensations apart.
research Targeting lymphoid-derived IL-17 signaling to delay skin aging
Blocking IL-17 signaling may reduce skin inflammation and delay aging.
research Principles and mechanisms of regeneration in the mouse model for wound‐induced hair follicle neogenesis
Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
research Regulation of melanocyte stem cells in the pigmentation of skin and its appendages: Biological patterning and therapeutic potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research Wnt10b Promotes Differentiation of Mouse Hair Follicle Melanocytes
Wnt10b helps hair follicle cells mature and produce pigment.
research Dermal white adipose tissue: a new component of the thermogenic response
Skin fat helps with body temperature control and has other active roles in health.
research Module-based complexity formation: periodic patterning in feathers and hairs
The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
research Transformation of amnion epithelium into skin and hair follicles
Mouse amnion can turn into skin and hair follicles with help from certain cells and factors.
research Smad4-dependent desmoglein-4 expression contributes to hair follicle integrity
Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.
research Accelerated Endothelial to Mesenchymal Transition Increased Fibrosis via Deleting Notch Signaling in Wound Vasculature
Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
research Development and Homeostasis of the Skin Epidermis
The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.
research Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling
Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
research Generation of Tβ4 knock-in Cashmere goat using CRISPR/Cas9
Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.
research Mesenchyme governs hair follicle induction
The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
research Epidermal Notch1 recruits innate lymphoid cells to orchestrate normal skin repair
Notch1 helps skin heal by attracting cells that aid repair.