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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
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June 2017 in “Journal of Investigative Dermatology” HPV8 causes skin cancer by expanding specific skin stem cells.
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May 2019 in “PLOS ONE” The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.
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June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
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August 2024 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” Single-cell transcriptomics helps improve animal health and productivity by studying gene expression in individual cells.
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January 2017 in “Stem Cells International” Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.
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June 2008 in “Journal of Investigative Dermatology” HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
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January 2019 in “Experimental Dermatology” Certain cells outside the hair follicle's bulge area can quickly regenerate damaged hair follicles, potentially helping to reduce hair loss from cancer treatments.
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February 2007 in “Journal of Investigative Dermatology” Deleting Rac1 in the skin depletes stem cells and damages hair follicles.
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July 2024 in “Frontiers in Oncology” New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
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May 2021 in “Journal of Cell Science” N1-acetylspermidine promotes hair follicle stem cell self-renewal.
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March 2018 in “Journal of Sociology” The anti-ageing treatment market is growing by exploiting fears of ageing with unproven promises, which could harm public trust and genuine science.
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June 2011 in “Nature Biotechnology” Stem cell treatments can potentially treat baldness, with one trial showing hair growth after injecting a hair-stimulating complex, and no safety issues were reported.
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August 2023 in “Frontiers in Cardiovascular Medicine” New methods improve stem cell delivery for heart disease, but challenges remain.
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August 2016 in “Journal of Visualized Experiments” The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.
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February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.
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March 2020 in “International Journal of Molecular Sciences” Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.