236 citations
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January 1951 in “Physiological zoology” Hair growth and pigmentation in mice involve specific stages crucial for research.
231 citations
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December 1999 in “Journal of Investigative Dermatology” Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.
220 citations
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August 1988 in “Clinical endocrinology” Melatonin may help with sleep issues, depression, and cancer, but more research is needed.
214 citations
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April 2017 in “Cell” Different small areas within hair follicles send specific signals that control what type of cells stem cells become.
209 citations
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October 2018 in “Cell Reports” Lgr5 and Lgr6 stem cells quickly adapt to help heal wounds.
208 citations
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December 2003 in “Journal of Investigative Dermatology” Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.
205 citations
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April 2005 in “Journal of Investigative Dermatology” Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.
196 citations
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March 2016 in “Nature Communications” Genetic factors influence hair traits like shape, color, and greying in Latin Americans.
182 citations
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May 2003 in “Development” Myc activation reduces skin stem cells by affecting cell adhesion.
178 citations
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May 2006 in “Developmental Dynamics” Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
169 citations
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January 2018 in “Cell Reports” Scientists grew hair follicles from mouse stem cells in a lab setting.
162 citations
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July 2011 in “Biomacromolecules” Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.
157 citations
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May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
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December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
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June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
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October 2016 in “Nanomedicine: Nanotechnology, Biology and Medicine” Fullerenes show potential in skin care but need more safety research.
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March 2011 in “Stem Cell Reviews and Reports” Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
90 citations
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June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
89 citations
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November 2017 in “Journal of Cellular Physiology” The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.
82 citations
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February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
82 citations
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December 2011 in “Journal of Biological Chemistry” p63 is essential for skin cell growth and differentiation by controlling specific gene networks.
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September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
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June 2007 in “PLoS ONE” Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.
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July 2016 in “New phytologist” The protein RSL4 is crucial for making root hairs longer by controlling genes related to cell growth.
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January 2023 in “International Journal of Biological Sciences” Engineered exosomes show promise for improving wound healing but face challenges in clinical use.
65 citations
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July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
65 citations
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October 2018 in “Frontiers in cellular and infection microbiology” Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.
65 citations
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January 2018 in “Nature Reviews Endocrinology” Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
64 citations
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August 2014 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.