185 citations
,
February 2018 in “Journal of Investigative Dermatology” Melatonin may benefit skin health and could be a promising treatment in dermatology.
94 citations
,
June 2016 in “The FASEB Journal” The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.
Folate salts penetrate skin well and improve wound healing, suggesting potential for skin treatments.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” Exosome therapy shows promise for hair growth with minimal side effects, but more research is needed.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
136 citations
,
April 2013 in “Clinical Cancer Research” The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.
100 citations
,
September 2016 in “Clinical transplantation/Clinical transplantation.” Voriconazole can cause serious side effects, especially in long-term use.
83 citations
,
March 2015 in “International Journal of Dermatology” ADSC-CM treatment improved hair density and thickness in women with hair loss, safely and effectively.
77 citations
,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
72 citations
,
January 2001 in “Drugs” Minoxidil and finasteride treat hair loss; more research needed for other options.
70 citations
,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
66 citations
,
May 2021 in “Science Advances” Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
64 citations
,
August 2013 in “Mayo Clinic Proceedings” Wound healing insights can improve regenerative medicine.
60 citations
,
January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
56 citations
,
January 2007 in “Pharmaceutical Development and Technology” Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.
54 citations
,
October 2002 in “Journal of controlled release” Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.
52 citations
,
January 2020 in “Scientific Reports” NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
51 citations
,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
50 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
42 citations
,
February 2021 in “Signal Transduction and Targeted Therapy” Hair follicle regeneration possible, more research needed.
40 citations
,
August 2022 in “Frontiers in immunology” Blocking JAK/STAT pathways can help treat hair loss from alopecia areata.
38 citations
,
February 2016 in “Surgery Journal” Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.
37 citations
,
February 2009 in “Bioorganic & Medicinal Chemistry” Finasteride complexes with HPβCD and polymers improve solubility, potentially enhancing hair loss treatment.
29 citations
,
September 2024 in “AAPS PharmSciTech” Transcutol® helps drugs penetrate the skin more effectively in various formulations.
28 citations
,
September 2015 in “Wiener Klinische Wochenschrift” New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.
27 citations
,
March 2018 in “Fertility and Sterility” Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.
25 citations
,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
25 citations
,
July 2015 in “Colloids and Surfaces B: Biointerfaces” Iontophoresis improves minoxidil delivery to hair follicles for hair loss treatment.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.