research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
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research The repairing of full-thickness skin deficiency and its biological mechanism using decellularized human amniotic membrane as the wound dressing
Human amniotic membrane helps heal skin wounds faster and with less scarring.
research Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis
Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
research Improving the anti-ageing activity of coenzyme Q10 through protransfersome-loaded emulgel
The method improved CoQ10's stability and effectiveness for anti-ageing skincare.
research Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation
Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
research Advanced Inhibition of Undesired Human Hair Growth by PPARγ Modulation?
GMG-43AC may help reduce unwanted hair growth and treat certain hair loss conditions.
research Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration
Pro-IGF-II improves muscle repair in old mice.
research Induction of osteoblastic differentiation of neural crest-derived stem cells from hair follicles
Hair follicle cells can become bone-like cells, useful for bone repair.
research Glutamic acid promotes hair growth in mice
Glutamic acid helps increase hair growth in mice.
research Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms
Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.
research Epidermal growth factor, innovation and safety
Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
research t-Flavanone Improves the Male Pattern of Hair Loss by Enhancing Hair-Anchoring Strength: A Randomized, Double-Blind, Placebo-Controlled Study
t-Flavanone helps improve male pattern hair loss by making hair roots stronger.
research Biocompatible ZnO nanoflower-infused chitosan/alginate/PVA composite for accelerated skin regeneration
The composite speeds up skin healing and is safe for use in wound dressings.
research A Signature of Genes Featuring FGF11 Revealed Aberrant Fibroblast Activation and Immune Infiltration Properties in Keloid Tissue
Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.
research Mucosal TLR5 activation controls healthspan and longevity
Activating TLR5 in the gut can extend lifespan and improve health in aged mice.
research Applications of Mesenchymal Stem Cells in Anti-Aging and Skin Regeneration
Mesenchymal stem cells can help delay skin aging and improve wound healing.
research Translational research in the generation of therapeutic medicine for wound healing: a review
New therapies show promise for wound healing, but more research is needed for safe, affordable options.
research Trajectory of hiPSCs derived neural progenitor cells differentiation into dermal papilla-like cells and their characteristics
Human stem cells were turned into cells similar to those that help grow hair and showed potential for hair follicle formation.
research Influence of donor sources and culture media on the histo-morphological quality of human artificial skin models
EpiLife® media and younger donor age improve artificial skin model quality.
research Regeneration of skin appendages and nerves: current status and further challenges
Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
research Dermal niche signaling and epidermal stem cells
Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
research Applications of Engineered Skin Tissue for Cosmetic Component and Toxicology Detection
Engineered skin tissue is a promising tool for safer cosmetic testing.
research Fibroblasts: Origins, definitions, and functions in health and disease
Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
research Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture
TNFα helps grow and maintain liver cells in 3D culture for a long time.
research Engineering strategies to enhance the research progress of mesenchymal stem cells in wound healing
Engineering strategies improve stem cells' ability to heal wounds effectively.
research Keratin intermediate filaments in the colon: guardians of epithelial homeostasis
Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
research 779 Multicellular skin organoids as a unique modeling platform for skin physiology, injury, and disease
The new skin organoid system effectively mimics human skin for studying its functions, injuries, and diseases.
research Mesenchymal Stem Cells for Regenerative Medicine
Mesenchymal stem cells can help repair body tissues with low risk of rejection.
research 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
3D bioprinting with special hydrogels helps heal wounds and grow new blood vessels.