research Un(MaSC)ing Stem Cell Dynamics in Mammary Branching Morphogenesis
Mammary stem cells drive mammary gland growth by branching and cell mixing.
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research Clinical Efficacy of SPARC-Modified Mesenchymal Stem Cells for the Treatment of Dog Skin Wounds
SPARC-modified stem cells significantly improve dog skin wound healing.
research Optimization of photobiomodulation therapy for spinal cord injury: A review
Standardizing light therapy methods could improve spinal cord injury treatment.
research The composition of cell‐based therapies obtained from point‐of‐care devices/systems which mechanically dissociate lipoaspirate: a scoping review of the literature
It's unclear if cell-based therapies from lipoaspirate devices improve clinical outcomes due to inconsistent data.
research Coordination of force-generating actin-based modules stabilizes and remodels membranes in vivo
Actin filaments help stabilize and reshape cell membranes.
research Alcohol and Prostate Cancer: Time to Draw Conclusions
Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.
research Application of multi-omics techniques to androgenetic alopecia: Current status and perspectives
Multi-omics techniques help understand the molecular causes of androgenetic alopecia.
research Protective Mechanism of Adipose-Derived Stem Cells in Remodelling of the Skin Stem Cell Niche During Photoaging
Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.
research Cutaneous wound healing: recruiting developmental pathways for regeneration
Understanding developmental pathways can improve wound healing treatments.
research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
research Control by a hair’s breadth: the role of microRNAs in the skin
MicroRNAs play a crucial role in skin and hair health, affecting everything from growth to aging, and could potentially be used in treating skin diseases.
research Body composition changes and inhibition of fat development in vivo implicates androgen in regulation of stem cell lineage allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
research The concealed side of caspases: beyond a killer of cells
Caspases do more than kill cells; they also help in cell growth and disease, and targeting them could lead to new treatments.
research Deciphering the Mesodermal Potency of Porcine Skin-Derived Progenitors (SKP) by Microarray Analysis
Pig skin cells can turn into mesodermal cells but lose their ability to become neural cells.
research Effective high-throughput isolation of enriched platelets and circulating pro-angiogenic cells to accelerate skin-wound healing
Angio PRP speeds up skin wound healing and reduces inflammation.
research SPT6 maintains epidermal homeostasis by inhibiting an NF-κB-positive feedback loop to prevent excessive inflammation
SPT6 prevents excessive skin inflammation by blocking a feedback loop.
research Do men’s faces really signal heritable immunocompetence?
Masculine facial features may not reliably indicate heritable health, and more research is needed.
research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development
The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
research Targeting the Wnt pathways for therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Novel therapeutic approaches in utilizing platelet lysate in regenerative medicine: Are we ready for clinical use?
Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
research Expression and roles of steroidogenic acute regulatory (StAR) protein in ‘non-classical’, extra-adrenal and extra-gonadal cells and tissues
The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.
research Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia
Androgens prevent hair growth by changing Wnt signals in cells.
research Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity
Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.
research Isolation of epithelial stem cells from dermis by a three-dimensional culture system
Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
research Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies
New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Insights learned from L457(3.43)R, an activating mutant of the human lutropin receptor
The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.
research Solanum nigrum L. in COVID-19 and post-COVID complications: a propitious candidate
Solanum nigrum shows promise for treating COVID-19 and its complications, but more research is needed.