The skin can still regenerate and function well even with fewer fibroblasts.
July 2025 in “Genome biology” HT-scCAT-seq helps understand gene regulation in embryonic skin development.
Lhx2 is a crucial regulator of the Sonic Hedgehog signaling in early mouse retinal development.
91 citations
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November 2008 in “Journal of biological chemistry/The Journal of biological chemistry” DGAT1 enzyme is crucial for healthy skin and hair by regulating retinoid levels.
53 citations
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September 2013 in “Journal of Investigative Dermatology” Hair follicle cells help protect against immune attacks by regulating T-cell activity.
September 2020 in “Research Square (Research Square)” Long noncoding RNAs help regulate hair follicle density in rabbits.
181 citations
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January 2019 in “Cell” Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.
133 citations
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September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
44 citations
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October 2019 in “International Journal of Molecular Sciences” Melatonin, usually known for sleep regulation, also has antioxidant properties that can protect skin, stimulate hair growth, and improve skin conditions, with topical application being more effective than oral use.
34 citations
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August 2019 in “Journal of Allergy and Clinical Immunology” mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.
21 citations
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October 2017 in “Cell death and disease” Sesn2 protects inner ear hair cells from damage by regulating certain cell survival pathways.
21 citations
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December 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.
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November 2019 in “Stem Cells” Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
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October 2017 in “Oncotarget” Gsdma3 affects hair growth by controlling Wnt5a, which influences hair cell development.
10 citations
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May 2020 in “Frontiers in cell and developmental biology” MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
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June 2024 in “Cell Reports” Hair follicles play a crucial role in regulating skin barrier function.
7 citations
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July 2024 in “Current Issues in Molecular Biology” Understanding skin stem cells and their regulation is key to improving skin healing and treating disorders.
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January 2010 in “Animal” Angora goat hair grows faster and produces more protein than cashmere goat hair, and certain hormones and nutrients positively affect hair growth and protein synthesis.
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April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Aging skin shows thinner layers, fewer hair follicles, and new biomarkers like increased space between cells and smaller sebaceous glands.
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July 2019 in “Research Square (Research Square)” Yak hair growth is influenced by genes and hormones, helping them adapt to alpine environments.
1 citations
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August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.
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August 2023 in “Cutis” Low ferritin levels can indicate iron deficiency as a cause of hair loss.
1 citations
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January 2021 in “Journal of biological chemistry/The Journal of biological chemistry” FLCN helps control iron levels in cells.
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January 2011 in “Springer eBooks” Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
March 2026 in “BioScience Trends” UV radiation causes skin aging by damaging cells and triggering harmful processes.
March 2026 in “International Journal of Science and Research (IJSR)” Melatonin protects skin and supports hair growth.
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
PPARβ/δ helps yaks adapt to high altitudes by regulating lipid metabolism in their coats.
October 2025 in “Journal of Investigative Dermatology” Hair follicle dermal stem cells help control hair growth timing by regulating signals at the hair germ–dermal papilla interface.
August 2024 in “Journal of Clinical Medicine” PRP shows promise but lacks consistent evidence and regulation.