research Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin
Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
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research Epidermal stem cells: practical perspectives and potential uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Epoxy Fatty Acids and Inhibition of the Soluble Epoxide Hydrolase Selectively Modulate GABA Mediated Neurotransmission to Delay Onset of Seizures
EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.
research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine
The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
research Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD
Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Genome-wide association study in Japanese females identifies fifteen novel skin-related trait associations
Researchers found 15 new genetic links to skin traits in Japanese women.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research Stem cell plasticity enables hair regeneration following Lgr5+ cell loss
Hair can regrow after certain stem cells are lost because other stem cells can take over their role.
research The Functional Diversity of Epidermal Keratins Revealed by the Partial Rescue of the Keratin 14 Null Phenotype by Keratin 16
K16 can partially replace K14 but causes hair loss and skin issues.
research Type 1 interferon signature in the scalp lesions of alopecia areata
Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.
research Hyperandrogenism in polycystic ovarian syndrome and role of CYP gene variants: a review
Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
research Targeted Disruption of Stat3 Reveals a Major Role for Follicular Stem Cells in Skin Tumor Initiation
Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
research Hair follicles, their disorders and their opportunities
Hair follicles offer promising targets for delivering drugs to treat hair and skin conditions.
research Hair follicle and interfollicular epidermal stem cells make varying contributions to wound regeneration
Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
research A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research Functional hair follicle regeneration: an updated review
Hair follicle regeneration possible, more research needed.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.
research Drug Repurposing - Hypothesis, Molecular Aspects and Therapeutic Applications
Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.
research TCL1 transgenic mouse model as a tool for the study of therapeutic targets and microenvironment in human B-cell chronic lymphocytic leukemia
The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
research Minoxidil improves vascular compliance, restores cerebral blood flow, and alters extracellular matrix gene expression in a model of chronic vascular stiffness
Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.
research Multifaceted role of hair follicle dermal cells in bioengineered skins
Human hair follicle dermal cells can effectively replace other cells in engineered skin.
research Effects of Subchronic Finasteride Treatment and Withdrawal on Neuroactive Steroid Levels and Their Receptors in the Male Rat Brain
Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.
research Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation
Prominin-1 expressing cells in the dermal papilla help regulate hair follicle size and communication but don't aid in skin repair.
research Hair removal using an Nd: YAG laser system.
Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
research Adipose stem cells isolated from diabetic mice improve cutaneous wound healing in streptozotocin-induced diabetic mice
Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
research Role of stem/progenitor cells in reparative disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Sarcoptic mange outbreak decimates South American wild camelid populations in San Guillermo National Park, Argentina
Sarcoptic mange nearly wiped out vicuñas and guanacos in an Argentine park.
research Biochemistry of epidermal stem cells
The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
research Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease
Mutations in certain receptors can cause diseases and offer new treatment options.