September 2024 in “Portuguese Journal of Dermatology and Venereology” CCCA and LPP may be related hair loss conditions influenced by genetics and environment, needing early treatment.
29 citations
,
September 2014 in “American Journal of Dermatopathology” Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.
14 citations
,
January 2011 in “Journal of Cutaneous Pathology” CK15 is not a reliable marker for stem cells in damaged hair follicles from patients with CCCA.
1 citations
,
July 2018 in “Journal of The American Academy of Dermatology” Sebaceous glands are often preserved and PPARy expression is constant in some cases of Central Centrifugal Cicatricial Alopecia.
September 2022 in “Skin appendage disorders” Seborrheic dermatitis may contribute to the development of central centrifugal cicatricial alopecia.
July 2008 in “British Journal of Dermatology” Cyclosporin doesn't stop hair loss.
7 citations
,
May 2005 in “Experimental Dermatology” Two mouse mutations cause similar hair loss despite different skin changes.
3 citations
,
May 2024 in “Amino Acids” Disrupted cysteine metabolism may cause hair breakage in Alopecia Areata, suggesting potential treatments like N-acetylcysteine.
15 citations
,
March 2015 in “Australasian Journal of Dermatology” Seborrhoeic dermatitis may cause a condition called "seborrhoeic folliculitis," leading to chronic scalp inflammation and scarring hair loss.
April 2024 in “Frontiers in medicine” Alopecia Areata significantly lowers quality of life and current treatments are inadequate, highlighting a need for better therapies and standardized treatment protocols.
27 citations
,
September 2018 in “Skin appendage disorders” Hair transplantation may work for some types of scarring alopecia, but results vary and more research is needed.
1 citations
,
July 2018 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
November 2025 in “Journal of Investigative Dermatology” Genetic variants in specific genes cause central centrifugal cicatricial alopecia.
56 citations
,
September 2010 in “Veterinary pathology” Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.
May 2017 in “InTech eBooks” Some hair loss disorders cause permanent loss due to scarring, and treatments like steroids don't always work well.
6 citations
,
August 2022 in “Dermatologic therapy” PRP therapy can temporarily grow hair in CCCA patients but isn't a permanent cure.
1 citations
,
December 2023 in “JAAD International” Mast cells may significantly contribute to central centrifugal cicatricial alopecia.
November 2025 in “PubMed” Genetic variants in specific genes cause a type of hair loss.
January 2019 in “Skin appendage disorders” A woman's hair loss was linked to a rare hormone-secreting ovarian tumor, treated with surgery and hair loss medication.
September 2017 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” CCCA and lichen planopilaris have similar histological features, making them hard to distinguish.
15 citations
,
September 2014 in “Journal of The American Academy of Dermatology” Seven patients were misdiagnosed with discoid lupus instead of lichen planopilaris due to similar symptoms, showing the need for careful diagnosis in scarring hair loss conditions.
2 citations
,
January 2025 in “JAAD Case Reports” Topical metformin may improve hair regrowth in CCCA when added to standard treatments.
19 citations
,
January 2015 in “Skin appendage disorders” The report found a new type of hair loss in African-American women that affects more areas of the scalp than previously thought.
170 citations
,
December 2009 in “Histopathology” The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.
April 2024 in “Journal of the American Academy of Dermatology” Diagnosing and treating CCCA requires understanding multiple causes and using various diagnostic tools.
22 citations
,
January 2018 in “Experimental Dermatology” The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.
19 citations
,
February 2013 in “The American Journal of Dermatopathology” Nonscarring alopecia has higher hair density than scarring alopecia, and hair density can help diagnose the type of alopecia.
5 citations
,
February 2019 in “The New England Journal of Medicine” Certain mutations in the PADI3 gene may increase the risk of developing a type of scarring hair loss common in women of African descent.
3 citations
,
October 2019 in “JAAD Case Reports” Two patients with lupus had an unusual type of hair loss not typical for the disease but improved with treatment.
1 citations
,
April 2010 in “Expert Review of Dermatology” The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.