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510-540 / 1000+ resultsresearch Crystal structure of Steroid 5-alpha-reductase 2 in complex with Finasteride
research In the eye of the beholder
Cosmeceuticals may have potential but their effectiveness and market success are still uncertain.
research Chemistry42: An AI-Driven Platform for Molecular Design and Optimization
Chemistry42 effectively creates and optimizes new molecules for drug discovery.
research Finasteride for Chronic Central Serous Chorioretinopathy
research Reverse Protein Engineering Of Firefly Luciferase
The protein's size was reduced, but more work is needed to confirm its function.
research Minoxidil
research Minoxidil
research DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation
The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.
research Nitrogen‐Boosted H 2 O 2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration
A new nanozyme using EGCG and L-arginine boosts hair growth by safely increasing beneficial oxidative stress.
research Steroid sulfatase inhibitors
Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.
research Biochemical features of primary cells from a pediatric patient with a gain-of-function ODC1 genetic mutation
A new genetic disorder caused by an ODC1 mutation can be treated with DFMO.
research Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.
Overexpressing COX-2 in mice skin reduces skin tumor development.
research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate
A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
research Docetaxel, cisplatin and 5-fluorouracil in patients with locally advanced unresectable head and neck cancer: a phase I–II feasibility study
The treatment combining docetaxel, cisplatin, and 5-FU is feasible and effective for advanced head and neck cancer.
research Biological properties of polycaprolactone and barium titanate composite in biomedical applications
Polycaprolactone and barium titanate composites show promise for use in biomedical applications.
research Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features
A new genetic mutation in the ODC1 gene causes developmental delay and other symptoms in a young girl.
research Using Precise Objectives to Enhance Student Achievement in Health Education.
Precise objectives can improve student achievement in health education.
research Label-Free Automated Cell Tracking: Analysis of the Role of E-cadherin Expression in Collective Electrotaxis
E-cadherin is important for cell movement in electric fields, and the new tracking method works well.
research Formation of the cornified envelope
The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.
research Exploring the therapeutic potential of Selaginella doederleinii extract for cervical cancer treatment through network pharmacology and in vitro studies
Selaginella doederleinii extract shows potential for cervical cancer treatment but needs more research.
research Doing Well by Doing Good: The Benevolent Halo of Corporate Social Responsibility
Corporate social responsibility can improve consumer ratings of product performance, especially when the company is seen as benevolent and consumers aren't experts on the product.
research The complex relationship between TFEB transcription factor phosphorylation and subcellular localization
Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.
research MON-913 Testosterone Secreting Ovarian Tumor: A Rare Cause of Erythrocytosis and Pulmonary Embolus
A rare ovarian tumor that produced testosterone caused a blood clot in the lungs and increased red blood cells in a woman.
research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development
Ozone therapy might improve cancer treatment and reduce its side effects.
research VICE-PRESIDÊNCIA FEDERATIVA DO BRASIL: UM INSTRUMENTO ESTRATÉGICO OU UMA “PEÇA DECORATIVA” GOVERNAMENTAL?
The text discusses whether Brazil's Vice-Presidency is a strategic tool or just a ceremonial government position.
research Stem Cells in Ophthalmology
research Abstract 1489: Basal cell carcinomas express functional indoleamine 2,3-dioxygenase (IDO) which may confer immunoprotection
Basal cell carcinomas may use IDO to protect themselves from the immune system.
research Bicalutamide
research Dwarf planet Ceres and the ingredients of life
The Dawn spacecraft found that Ceres has complex organic molecules and a lot of water ice, hinting it might support life.