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Epiprofin suppresses parathyroid hormone gene activity, helping regulate calcium levels and could be a treatment target for hyperparathyroidism.

CLK1 is needed for skin cells to become epidermal cells but not sebocytes.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.

Mutations in Far2 mice cause hair loss due to sebaceous gland issues.

DcR3 helps heal wounds and regrow hair by changing macrophages to a repair-focused type.

Activated β-catenin affects hair growth and skin thickness, and changes are reversible.

Qing Cuo Formula may effectively treat acne by reducing inflammation and hormone levels.

Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.

A man with kidney tumors and lung cysts was diagnosed with Birt–Hogg–Dubé syndrome and treated successfully, with genetic testing confirming the diagnosis.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Claudin-1 is important for the barrier function and growth of hair.

A new Wnt surrogate specifically targets the Frizzled7 receptor, promoting organoid formation and hair growth.

Early use of infliximab in severe pediatric Crohn's disease can lead to significant improvement and remission.

The S250C variant in a gene may cause autoimmunity and immunodeficiency by impairing protein function.

A high-fat diet worsens neutrophilic folliculitis by increasing certain chemokines.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

CRISPR/Cas systems show promise for cancer treatment by targeting miRNAs, but delivery and specificity challenges remain.

Cathepsin L is essential for normal hair growth and development.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Some skin growths with mucin can form hair follicles and resemble skin cancer, but a special stain can help tell them apart.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

PDGFC gene may help select goats with desirable curly wool traits.

5α-reductase deficiency can cause ambiguous genitalia and gender dysphoria, treatable with testosterone.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Rat hair follicle stem cells have functional oxytocin receptors, useful for studying neuropsychiatric disorders.

TMPRSS2 affects COVID-19 severity and treatment options.

PrrH sRNA controls pyochelin gene expression in Pseudomonas aeruginosa based on heme levels.