research Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity
Compounds from the plant Mammea siamensis may help treat hair loss.
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research Regulation of Semaphorin3A in the process of cutaneous wound healing
Sema3A can both slow and speed up wound healing, depending on its form and combination with EGF.
research Metabolic dysfunction in female mice with disruption of 5α-reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
research The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis
Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
research LRIG1 is a positive prognostic marker in Merkel cell carcinoma and Merkel cell carcinoma expresses epithelial stem cell markers
LRIG1 is linked to better survival in Merkel cell carcinoma.
research Flutamide-Loaded Zein Nanocapsule Hydrogel, a Promising Dermal Delivery System for Pilosebaceous Unit Disorders
The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.
research Effects of flavonoid derivatives on human microvascular endothelial cells
Some flavonoids may help with hair growth by affecting blood vessel function in hair follicles.
research Effectiveness of the combinational treatment ofLaminaria japonicaandCistanche tubulosaextracts in hair growth
Laminaria japonica and Cistanche tubulosa extracts combined may effectively promote hair growth.
research Effect of finasteride particle size reduction on its pharmacokinetic, tissue distribution and cellular permeation.
Smaller finasteride particles increase effectiveness in treating hair loss.
research Core-shell nanocarriers based on PEGylated hydrophobic hyperbranched polyesters
The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
research Development of finasteride polymer microspheres for systemic application in androgenic alopecia
Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
research Modulating testosterone pathway: a new strategy to tackle male skin aging?
Honokiol might help reduce male skin aging by maintaining testosterone levels.
research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
research Sub-chronic effects of a Phthirusa pyrifolia aqueous extract on reproductive function and comparative hormone levels in male rats
Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.
research Development of fluridil, a topical suppressor of the androgen receptor in androgenetic alopecia
Fluridil promotes hair growth safely and effectively for androgenetic alopecia.
research Skin biology
Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
research Acne
Acne is a common skin condition that can be influenced by diet, lifestyle, and hormones, and requires a treatment approach that includes psychological considerations.
research CARAWAY, CHINESE CHIVES AND CASSIA AS FUNCTIONAL FOODS WITH CONSIDERING NUTRIENTS AND HEALTH BENEFITS
Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.
research Epidemiological Assessment of Testosterone Levels in Women Population: A Factorial Analysis of Cell Proliferation
High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.
research The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids
Low dose finasteride decreases certain steroids, possibly increasing depression risk.
research Androgenic Efficacy and Mechanism of Glycosides-Based Standardized Fenugreek Seeds Extract Through Aromatase And 5-Alpha Reductase Inhibition
Fenugreek seed extract boosts testosterone and improves male reproductive health without heart side effects.
research The Impact of the 5α-Reductase Inhibitors (5α-RIs) on Male Sexual Function and Psychological Well-Being
5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.
research Immunohistochemical Study on the Hair Growth Promoting Effect of Yonnyuniksoogobon-dan
Yonnyuniksoogobon-dan taken orally promotes hair growth by affecting growth factors in hair roots.
research Dendrobium officinale polysaccharide improves hair regrowth in androgenetic alopecia mice and is associated with coordinated changes in local steroid metabolism, ESR1 activation, and keratin-related follicular responses
Dendrobium officinale polysaccharide helps hair regrowth in hair loss mice by affecting local steroid metabolism and hair follicle responses.
research Skin manifestations of hyperandrogenism: an update
Targeting androgen receptors in the skin is the most effective treatment for hyperandrogenism-related skin issues.
research Exploring the Mechanism of Platycladi Cacumen in Intervening Androgenetic Alopecia Based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation
Platycladi Cacumen may help treat hair loss by targeting specific proteins and pathways.
research Licorice: A review on phytochemical insights and therapeutic potential
Licorice has health benefits but can also cause side effects, so it should be used carefully.
research The role of microneedling in treatment of melasma
Microneedling may improve melasma treatment by boosting topical therapy effectiveness.
research The Drug Reboot: Finding New Life in Old Formulations
Repurposing existing drugs can quickly and cheaply find new treatments for diseases.
research Recent approaches of antibody therapeutics in androgenetic alopecia
Antibody treatments show promise for hair loss but need more research.