April 2017 in “Journal of Investigative Dermatology” The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” M2 macrophages help hair regrowth in wounds by making growth factors.
September 2007 in “Journal of Investigative Dermatology” ANp63 is crucial for skin integrity, new filaggrin gene mutations link to eczema, hair can regrow from non-stem cells, sunburns are increasing, and glucocorticoids help treat skin allergies by affecting immune cells.
124 citations
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February 2018 in “Nature Reviews Genetics” Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.
20 citations
,
June 2010 in “Genes and Immunity” Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
March 2026 in “Preprints.org” Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.
January 2026 in “Frontiers in Molecular Biosciences” A new method helps diagnose alopecia areata using specific gene markers and could guide targeted treatments.
New insights into cell communication in psoriasis suggest innovative drug treatments.
December 2022 in “Research Square (Research Square)” Key genes linked to immune response are upregulated in hair follicles and skin tissues in chronic discoid lupus erythematosus.
October 2022 in “Research Square (Research Square)” Key genes linked to immune response are highly active in lupus-affected hair follicles.
April 2026 in “Metabolites” Chronic skin diseases and metabolic syndrome are linked by shared inflammation pathways.
489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
64 citations
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July 2016 in “Journal of Immunology” Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
51 citations
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October 2019 in “Cells” Baricitinib reduces inflammation and improves cell health in premature aging cells.
40 citations
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December 2016 in “Journal of Dermatological Treatment” JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
24 citations
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January 2012 in “Journal of Cellular Biochemistry” C-reactive protein helps monocytes stick to blood vessel cells by causing oxidative stress.
16 citations
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June 2017 in “Advances in Therapy” New treatments for hair loss are showing promise due to better understanding of genetics and the immune system.
14 citations
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October 2018 in “Brain Research Bulletin” Exosomes help nerve fibers grow by affecting specific cell signaling pathways.
9 citations
,
August 2021 in “Biological Chemistry” ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
4 citations
,
April 2025 in “Antioxidants” Alpha-ketoglutarate protects rabbit skin cells from oxidative damage by activating a specific cell pathway.
4 citations
,
November 2023 in “Frontiers in immunology” New treatments targeting T-cell pathways are needed for better alopecia areata management.
4 citations
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June 2023 in “Frontiers in Aging” Improving blood flow and oxygen levels in middle age may help prevent age-related diseases.
1 citations
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January 2025 in “Genes & Diseases” Understanding T cells and signaling pathways can lead to better treatments for hair loss.
1 citations
,
March 2024 in “Signal transduction and targeted therapy” NF-κB signaling is crucial in many diseases and can be targeted for new treatments.
1 citations
,
February 2023 in “International Journal of Molecular Sciences” Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.
1 citations
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February 2021 in “Farmacja Polska” Janus kinase inhibitors show promise in treating autoimmune skin diseases.
May 2026 in “International Journal of Molecular Sciences” Chemotherapy-induced hair loss may be linked to immune system changes, and certain treatments could help but need careful use.
December 2025 in “ADMET & DMPK” Personalized treatments for hair loss focus on specific genetic and biological pathways.
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
December 2025 in “Scientific Reports” Valproic acid helps hair follicle stem cells survive better in low oxygen and glucose conditions.