research A regulatory perspective on pharmacokinetic/pharmacodynamic modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
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research Simultaneous Determination of Quercitrin, Afzelin, Amentoflavone, Hinokiflavone in Rat Plasma by UFLC–MS-MS and Its Application to the Pharmacokinetics of Platycladus orientalis Leaves Extract
Researchers developed a method to measure plant compounds in rat blood and found they are quickly absorbed and eliminated within 36 hours.
research pH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption
Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.
research The Role of Interface Geometry and Appendages on the Mesoscale Mechanics of the Skin
Skin's uneven surface and hair follicles affect its stress and strain but don't change its overall strength, and help prevent the skin from peeling apart.
research On the geographies of hair: Exploring the entangled margins of the bordered body
Hair significantly shapes body identity and social interactions, influencing how we perceive and relate to our bodies.
research cDermo-1 misexpression induces dense dermis, feathers, and scales
cDermo-1 causes dense skin, feathers, and scales in chickens.
research Looking Back on 2025
In 2025, the journal focused on diverse, inclusive dermatology research and shared knowledge through various media.
research Investigation of exacerbating factors for postpartum hair loss: a questionnaire-based cross-sectional study
Long-term breastfeeding and preterm labor may worsen postpartum hair loss.
research Parity-related variation in cortisol concentrations in hair during pregnancy and in the postpartum period: a prospective cohort study
First-time mothers had higher stress hormone levels in late pregnancy than mothers who had given birth before.
research Ageing-Related Features of Hair and Scalp in Chinese Women by Clinical Evaluation Study
Chinese women's hair gets thinner and grayer with age, and scalp conditions change, especially after 40.
research Le tégument des vertèbres et la spécification de l'épithélium cornéen
The cornea develops independently of the lens, following its own default pathway.
research Clinical Management of Prostate Cancer in High-Risk Genetic Mutation Carriers
More research and guidelines are needed for managing prostate cancer in people with high-risk genetic mutations.
research m6A Methylation Analysis Reveals Networks and Key Genes Underlying the Coarse and Fine Wool Traits in a Full-sib Merino Family
Key genes and pathways influence wool traits in Merino sheep.
research Planar Proton Minibeam Irradiation Elicits Spatially Confined DNA Damage in a Human Epidermis Model
Proton minibeam radiotherapy may reduce skin side effects by causing localized DNA damage.
research Close Temporal Relationship between Oscillating Cytosolic K+ and Growth in Root Hairs of Arabidopsis
Potassium changes lead root hair growth, with calcium and other factors regulating the process.
research Methyl Jasmonate Activates the 2C Methyl-D-erithrytol 2,4-cyclodiphosphate Synthase Gene and Stimulates Tanshinone Accumulation in Salvia miltiorrhiza Solid Callus Cultures
Methyl jasmonate boosts tanshinone production in Salvia miltiorrhiza callus cultures.
research γδ T cells mediate a requisite portion of a wound healing response triggered by cutaneous poxvirus infection
γδ T cells are crucial for early wound healing after a skin virus infection.
research Suicidality Risks Associated with Finasteride, a 5-Alpha Reductase Inhibitor: An Evaluation of Real-World Data from the FDA Adverse Event Reports
Finasteride use may increase suicidality risk, especially in young men.
research Role of oral minoxidil in the treatment of androgenetic alopecia
Low-dose oral minoxidil can help treat male and female pattern hair loss, especially in those who can't use topical treatments or have heart health issues.
research Developmental Regulation of Prion Expression in Cattle and Mouse Embryonic Stem Cells
PrPC is important for neural differentiation in cattle and mouse embryonic stem cells.
research Scalp Seborrheic Dermatitis: What We Know So Far
Scalp seborrheic dermatitis is a common skin condition linked to oil production and bacteria, with specific diagnostic features and treatments like antifungals and corticosteroids.
research Hair Follicle Development and Cashmere Traits in Albas Goat Kids
Hair follicle traits at 6 months can help select cashmere goats for breeding.
research Sex Identification of Feather Color in Geese and the Expression of Melanin in Embryonic Dorsal Skin Feather Follicles
Female goslings have darker feathers than males due to more melanin.
research ‘Dr. Google, What Is That on My Skin?’—Internet Searches Related to Skin Problems: Google Trends Data from 2004 to 2019
More people are using Google to search for skin problems like itch, hair loss, and rashes.
research Cosmeceutical Therapy: Engaging the Repercussions of UVR Photoaging on the Skin’s Circadian Rhythm
Natural skincare products may help reduce sun damage and support the skin's daily cycle.
research Electronic States of Epigallocatechin-3-Gallate in Water and in 1,2-dipalmitoyl-sn-glycero-3-phospho-(1′-rac-glycerol) (Sodium Salt) Liposomes
EGCG shows strong electron transfer interactions when bonded to DPPG lipids.
research Hair Growth-Promoting Activities of Glycosaminoglycans Extracted from the Tunics of Ascidian (Halocynthia roretzi)
Substances from Ascidian tunics might help treat hair loss as effectively as Minoxidil.
research Peripubertal Testosterone, 17β-Estradiol and Progesterone Concentrations in Hair and Nails in Dobermann Dogs
Hair and nails can show hormone changes during puberty in dogs.
research Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity
The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
research De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes
The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.