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research Sustained release of inhibitor from bionic scaffolds for wound healing and functional regeneration
Researchers developed a scaffold that releases a healing drug over time, improving wound healing and skin regeneration.
research Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata
SCD-153 shows promise as an effective topical treatment for alopecia areata.
research Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b‐mediated chromatin demethylation
Kdm6b is crucial for skin cell differentiation.
research Special Biochemical Features of the Hair Follicle
Hair follicles have unique proteins that vary by species and are influenced by nutrition.
research Characterization and expression analysis of the hair keratin associated protein KAP26.1
research Establishment of dermal sheath cell line from Cashmere goat and characterizing cytokeratin 13 as its novel biomarker
Scientists created a new cell line from Cashmere goat hair and found that cytokeratin 13 is a unique marker for certain skin cells.
research Moisture sorption/desorption of protein fibres
Internal lipids in keratin fibers, like wool and hair, reduce water absorption and release.
research Preparation and characterization of keratin-based biocomposite hydrogels prepared by electron beam irradiation
Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.
research Ultrastructure of two types of glandular hairs of salvia farinacea benth during development
Capitate trichomes have more endoplasmic reticulum and vacuoles, while peltate trichomes have more plastids and larger subcuticular spaces.
research The Type I Keratin 19 Possesses Distinct and Context-dependent Assembly Properties
Keratin 19 forms less stable and shorter filaments than keratin 14, giving unique traits to certain skin cells.
research IMMUNOHISTOCHEMICAL EXPRESSION OF KERATIN PROTEINS IN KERATOACANTHOMAS OF THE SKIN
Keratoacanthomas and squamous cell carcinomas have similar keratin patterns, making them hard to tell apart.
research Self-aggregates of Hydrophobic Phospholipid Polymer as a Novel Material in Hair Treatment
PMS nanoparticles improve damaged hair by protecting and restoring its surface and color.
research 144 Deciphering the role of the hexosamine pathway in skin homeostasis
The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research pH STIMULUS-RESPONSIVE HYBRID NANOPARTICLES: A SYSTEM DESIGNED FOR FOLLICULAR DELIVERY OF BRAZILIAN PLANT-DERIVED 5-ALPHA-REDUCTASE ENZYME INHIBITORS
New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.
research Keratin metabolism in the epidermis and hair of mice with experimental diabetes
Diabetes changes keratin in skin and hair, affecting their health.
research Hypaphorine, an indole-3-acetic acid antagonist delivered by the ectomycorrhizal fungus Pisolithus tinctorius , induces reorganisation of actin and the microtubule cytoskeleton in Eucalyptus globulus ssp bicostata root hairs
Hypaphorine from a fungus changes the internal structure of Eucalyptus root hairs, stopping their growth.
research Proopiomelanocortin expression in the skin during induced hair growth in mice
research 307 Dermatologic toxicities associated with chronic gamma-secretase inhibitor treatment for desmoid tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
research An epidermis‐permeable dipeptide is a potential cosmetic ingredient with partial agonist/antagonist activity toward fibroblast growth factor receptors
Pro-Ile could be used in cosmetics to improve skin, hair growth, and healing.
research 130 Deciphering the role of the hexosamine pathway in skin homeostasis
The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.
research An osteopontin‐derived peptide inhibits human hair growth at least in part by decreasing fibroblast growth factor‐7 production in outer root sheath keratinocytes
FOL-005 peptide can reduce human hair growth by lowering FGF7 levels.
research Beyond Expectations
Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
research Keratin disorders: from gene to therapy
New treatments targeting specific genes show promise for treating keratin disorders.
research The ultrastructure of the interfollicular epidermis of the hairless (hr/hr) mouse
research Cartilage oligomeric matrix protein (COMP) forms part of the connective tissue of normal human hair follicles
A protein called COMP is part of the connective tissue in normal human hair follicles and may be important for hair health.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Localization and Expression of Cornifin-α/SPRR1 in Mouse Epidermis, Anagen Follicles, and Skin Neoplasms
research Escin Activates Canonical Wnt/β-Catenin Signaling Pathway by Facilitating the Proteasomal Degradation of Glycogen Synthase Kinase-3β in Cultured Human Dermal Papilla Cells
Escin may help treat hair loss by boosting a specific cell growth pathway.