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Activating cannabinoid receptor 1 may help manage psoriasis by reducing certain keratins.

Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.

EBV infection increases a specific keratin variant in carcinoma cells, possibly affecting cell structure and cancer progression.

Mutations in the KRT16 gene can cause skin and nail disorders.

Removing MCPIP1 from myeloid cells in mice leads to hair loss and prevents skin tumors but causes pigmented spots.

A new keratin gene was found in mice, explaining hair growth.

The study revealed the detailed structure of a keratin dimer, aiding understanding of how intermediate filament proteins function.

The HCR gene contributes to psoriasis risk.

The document introduced a new naming system for keratin-associated proteins to improve clarity and communication across species.

K15 and Id3 are important in hair follicle regeneration, with K15 increasing in early stages and Id3 responding later.

Removing Mediator 1 causes teeth cells to turn into hair cells.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

BMI1 is essential for preventing hair greying and maintaining hair color.

AGC2-1 protein is essential for root hair growth in Arabidopsis.

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

Ptprq has multiple forms that change during inner ear development.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

Laminin-511 is essential for proper melanocyte movement and development in mice.

Chronic graft-versus-host disease in the skin shows strong Th1 immune response and unique barrier issues.

Claudin-1 is crucial for maintaining skin barrier and preventing inflammation.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

A rare genetic deletion in the KRT1 gene causes unique skin symptoms in a family.

A gene mutation in mice causes skin defects and early death.

SKH1 hairless mice have identifiable epidermal stem cells with specific markers.

Keratin-associated proteins help link filaments and affect keratin's strength.

Mutant MK6a transgenes in mice cause blistering, hair loss, and potential human alopecia.

K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.

Loss of keratin K2 causes skin problems and inflammation.