102 citations
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September 1977 in “The Lancet” Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.
March 2024 in “Nutrients” Gynostemma pentaphyllum and its component damulin B could help hair grow by activating certain cell pathways.
December 2025 in “JEADV Clinical Practice” These new skin treatments are safer and more effective with minimal side effects.
May 2019 in “Journal of clinical oncology” Topical calcitriol was safe and well-tolerated for potential hair loss prevention in chemotherapy patients.
March 2005 in “Journal of The American Academy of Dermatology” The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
1 citations
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May 1992 in “Pharmacological Research” July 2026 in “Journal of the American Academy of Dermatology”
January 1987 in “Side effects of drugs annual” Some cosmetics and dermatological drugs can cause allergic reactions and side effects, like skin irritation and systemic issues.
May 2021 in “Zenodo (CERN European Organization for Nuclear Research)” Low-dose oral minoxidil can cause dry mouth.
37 citations
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December 2001 in “Journal of the American Academy of Dermatology” Thalidomide significantly improved hair regrowth in a woman with lichen planopilaris.
Low-dose oral minoxidil is generally safe for treating hair loss, with mostly mild side effects.
March 2016 in “Reactions Weekly” A woman experienced hair loss, nail changes, bone marrow suppression, and low blood protein after taking azathioprine.
9 citations
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July 2007 in “Journal of Investigative Dermatology” Claudin expression changes help the skin respond to injury.
February 2024 in “Practical Diabetes” Spironolactone helps reduce hospital visits and death from heart issues, lowers blood pressure, but has unclear effects on heart failure with normal heart pump function and can cause high potassium and breast enlargement in men.
September 2025 in “International Journal of Women’s Dermatology” Oral spironolactone effectively promotes hair growth in premenopausal women but may cause irregular menstruation.
July 2025 in “Journal of Investigative Dermatology” Low-dose oral minoxidil is safe for the heart in the short term for hair loss patients.
3 citations
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July 2023 in “International Journal of Trichology” DPCP can help regrow hair in some people with severe alopecia.
2 citations
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May 2022 in “Advanced therapeutics” A new microneedle system effectively delivers a vasodilator to hair follicles, promoting hair growth better than current treatments.
July 2025 in “Skin Appendage Disorders” Dutasteride microinfusion and microneedling both effectively treat male hair loss.
6 citations
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January 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil can be effective for hair loss but should be avoided in people with certain heart conditions and severe liver problems.
2 citations
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January 2009 in “Journal of Drug Delivery Science and Technology” Minoxidil in distearyldimethylammonium chloride vesicles significantly promotes hair growth, while minoxidil in microparticles or poloxamer solutions doesn't.
July 2025 in “Journal of Investigative Dermatology” AMP-303 safely increases hair growth in men with hair loss.
18 citations
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October 2018 in “Journal of The American Academy of Dermatology” Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.
Spironolactone effectively treats hormonal acne, hair loss, and excess hair growth in women.
9 citations
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June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
November 2025 in “Clinical and Translational Allergy” The consensus provides guidelines for safely stopping danazol in hereditary angioedema treatment.
September 2015 in “Photodiagnosis and Photodynamic Therapy”
Stopping minoxidil and draining fluid around the heart can save lives in rare cases.
16 citations
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April 2000 in “Contact dermatitis” A man developed severe skin reactions after using a treatment for hair loss.