research Non-clinical safety evaluation and risk assessment to human of aleglitazar, a dual PPAR α/γ agonist, and its major human metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
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research Fail-tests of DNA methylation clocks, and development of a noise barometer for measuring epigenetic pressure of aging and disease
Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.
research Cardiometabolic risk factors in women with non-classic congenital adrenal hyperplasia
Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.
research Post-Finasteride Syndrome: About 2 Cases and Review of the Literature
research HuR ablation destabilizes Foxp3 mRNA and impairs regulatory T cell function, contributing to an autoimmune phenotype
HuR is essential for Treg function and preventing autoimmunity.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research A Monoclonal Antibody Established from the Immunization of Basal Cell Carcinoma (BCC) Tissues Reacts to the Intercellular Space of BCC and Hair Follicles
The antibody created from BCC tissues reacts similarly to both BCC and hair follicles, suggesting BCC may come from hair follicle cells.
research Cosmetic aspects of cranial reconstruction
The article concludes that cranial reconstruction should aim for the best aesthetic result, using various techniques tailored to individual needs and conditions.
research ApoBDs: a paradigm shift from cellular debris to therapeutic vehicles
ApoBDs, once seen as waste, are now viewed as potential tools for disease treatment and tissue repair.
research Descriptive analysis of whole blood concentrations of toxic, essential, and trace elements in adult females from the MIREC-ENDO study
Most women had adequate essential elements except zinc, and lead levels were higher in peri-/post-menopausal women.
research A review on formulation and analytical aspect of mangiferin a natural phenolic xanthonoid
Improving mangiferin's solubility and delivery can enhance its health benefits.
research Bias Assessment and Data Drift Detection in Medical Image Analysis: A Survey
Reliable machine learning in medical imaging needs bias checks and data drift detection for consistent performance.
research A systematic review of the social impact of diseases in Nordic countries
Diseases have a big social impact in Nordic countries, affecting healthcare decisions.
research The coenzyme A precursor pantethine enhances antitumor immunity in sarcoma
Pantethine may boost the immune system's ability to fight sarcoma.
research TCM “medicine and food homology” in the management of post-COVID disorders
Traditional Chinese medicinal foods may help manage long-term post-COVID symptoms.
research NOVEL CORONAVIRUS (SARS-COV-2): MOLECULAR BIOLOGY, PATHOGENESIS, PATHOBIOLOGY AND ADVANCES IN TREATMENT OF COVID-19 PATIENTS– AN UPDATE
COVID-19 is caused by a virus from bats, and efforts focus on prevention and treatment research.
research Characterization of novel TMEM173 mutation with additive IFIH1 risk allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research Over-the-counter drugs against hair loss
Most over-the-counter hair loss treatments lack strong evidence of effectiveness, except for minoxidil, which works but stops working if you stop using it.
research Sexual desire in a sample of married Egyptian women with polycystic ovarian syndrome
Married Egyptian women with PCOS have lower sexual desire compared to those without PCOS.
research Anorexia Nervosa and Bulimia Nervosa
Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.
research Phytochemicals in the Management of Polycystic Ovary Syndrome, Endometriosis, and Menstrual Irregularities
Plant compounds may help manage PCOS, endometriosis, and menstrual issues.
research Formulasi Sediaan Hair Tonic Ekstrak Rumput Laut (Hormophysa Triquetra) Dengan Kombinasi Ekstrak Kemiri (Aleurites Moluccana) Sebagai Penumbuh Rambut
The hair tonic with the highest seaweed extract content showed the best hair growth results.
research Kajian Pustaka: Sediaan Kosmesetika Penumbuh Rambut dari Berbagai Herbal Nusantara
A hair tonic made from kale leaves is effective for hair growth and meets Indonesian standards.
research Immunopathogenesis of Primary Cicatricial Alopecia
Hair loss in Lichen Planopilaris is caused by immune system issues damaging hair follicles and stem cells.
research Notices
The document announced plastic surgery events and courses for late 1997.
research An ethnobotanical review of medicinal plants used for treating hemorrhoids in Thailand
Traditional Thai medicinal plants show promise for treating hemorrhoids.
research Prevalence and Clinical Spectrum of Dermatologic Conditions in Renal Transplant Recipients: A 10-Year Retrospective Cross-Sectional Study
Renal transplant recipients often have skin issues, especially infections, and need regular skin check-ups.
research Circulating MicroRNA Signatures in Severe Alopecia Areata: Diagnostic Discrimination, Pathway Analysis, and Therapeutic Implications
Distinct miRNA signatures could help diagnose and treat severe Alopecia Areata.
research Geriatric Dermatologic Therapy
Elderly skin care needs personalized treatment, early intervention, and integrated psychiatric care.
research What “regenerative” means in aesthetic medicine: a narrative literature review attempting to demystify the core essence of regenerative aesthetics
Regenerative aesthetic medicine aims to restore tissue function, but needs more consistent evidence and standardized practices.