research 603 Degradation of aberrant NETs by DNases is a promising therapeutic strategy for SJS/TEN
Using DNase enzymes to break down harmful NETs could be a new treatment for Stevens-Johnson syndrome and toxic epidermal necrolysis.
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180-210 / 1000+ results research Spinal bicuculline produces hypersensitivity of dorsal horn neurons: effects of excitatory amino acid antagonists
Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
research Research progress on the role of peripheral nerves in wound healing
Peripheral nerves are essential for skin wound healing and future treatments could improve by focusing on nerve and blood vessel regeneration.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research Cutaneous Neuroimmune Interactions in Peripheral Neuropathic Pain States
New therapies targeting skin neuroimmune interactions could treat neuropathic pain.
research Fine Structure of Perifollicular Nerve Endings in Human Hair
research Keratin Gel as Conduit Filler for Peripheral Nerve Regeneration on a Rat Sciatic Nerve Injury Model
Keratin gel may help repair damaged nerves.
research Regulation of itch-induced scratching by nucleus accumbens dopamine receptor-expressing neurons
Dopamine receptors in the brain influence itch-related scratching behavior.
research LB1059 Neuromediators associated with neurogenic skin inflammation promote M2 differentiation of macrophages in human skin ex vivo
Certain substances can help skin cells become anti-inflammatory, aiding in tissue repair.
research Growth of Nerve Fibers to Merkel Cells Observed in Co-Culture of Sensory Ganglia and Sinus Hair Follicles
Merkel cells likely attract sensory nerve fibers.
research Changes in intraepidermal nerve fiber and Langerhans cell densities in the plantar skin of rats after mercuric chloride exposure
Mercury exposure damages small nerve fibers in rats' skin.
research Molecular docking simulation studies on potent butyrylcholinesterase inhibitors obtained from microbial transformation of dihydrotestosterone
Metabolite 7 is a strong inhibitor for Alzheimer's disease management.
research Localization of mechanosensitive channel TRPV4 in mouse skin
TRPV4 helps sense pressure in mouse skin.
research Author response: The signaling lipid sphingosine 1-phosphate regulates mechanical pain
Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.
research Tissue‐engineering approaches to enhance nerve regeneration during wound healing
Two methods improved nerve regeneration and touch recovery in skin grafts for burn patients.
research Three-dimensional analysis of intraepidermal nerve fibres and Langerhans cells in keloids with a focus on pruritus
Itchy keloids on the chest are linked to more nerve fibers and substance P.
research Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle
Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
research The sensory innervation of primate facial skin. II. Vermilion border and mucosa of lip
Monkey lips have dense sensory nerves similar to those in other skin areas, explaining their sensitivity.
research Intravital Two-Photon Imaging of Touch Sensory Axon Morphology in Mouse Skin
A new imaging method helps see and study touch nerve endings in mouse skin.
research Exosomes from Hair Follicle Epidermal Neural Crest Stem Cells Promote Acellular Nerve Allografts to Bridge Rat Facial Nerve Defects
Exosomes from stem cells help improve nerve repair in rats.
research Sensitive skin
Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.
research Is neuronal inhibition or excitability controlled by Na+K+2CL– transporters?
NKCC1 transporters help control neuron excitability and inhibition.
research Human dermal fibroblast‐derived secretory proteins for regulating nerve restoration: A bioinformatic approach
Human dermal fibroblast proteins help restore nerves during healing.
research Characteristic Localization of Neuronatin in Rat Testis, Hair Follicle, Tongue, and Pancreas
Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.
research The structure and organization of lanceolate mechanosensory complexes at mouse hair follicles
Lanceolate complexes in mouse hair follicles are essential for touch and depend on specific cells for maintenance and regeneration.
research Decision letter: The signaling lipid sphingosine 1-phosphate regulates mechanical pain
Sphingosine 1-phosphate helps control mechanical pain.
research Poster 252 Patient Registry of Outcomes in Spasticity Care
The data suggests that dosing differences can help manage spasticity in patients with upper motor neuron dysfunction.
research Lysophosphatidic acid and signaling in sensory neurons
Lysophosphatidic acid affects sensory neurons and may cause neuropathic pain and itch.
research Effects of transient receptor potential (TRP) channel agonists and antagonists on slowly adapting type II mechanoreceptors in the rat sinus hair follicle
TRPA1 and TRPV1 channels don't affect mechanotransduction in rat sinus hair follicles.
research Experimental study on the compatibility and degradation of human hair keratin bridging for peripheral nerve defects
Human hair keratin is a promising material for nerve repair.