January 2019 in “Frontiers in neurology” A nutrition program significantly improved a woman's lupus symptoms.
Male marathon runners in their 40s and 50s had more hair loss and higher heavy metal levels.
January 2013 in “Kidney international” A man with kidney tumors and lung cysts was diagnosed with Birt–Hogg–Dubé syndrome and treated successfully, with genetic testing confirming the diagnosis.
467 citations
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October 2014 in “European Journal of Endocrinology” The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
305 citations
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July 2016 in “International Journal of Biological Macromolecules” Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.
211 citations
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March 2011 in “Journal of Lipid Research” A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.
158 citations
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January 2003 in “Journal of Forensic Sciences” Hair testing can detect a single GHB exposure, useful for documenting sexual assault.
157 citations
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May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
157 citations
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June 2015 in “Psychoneuroendocrinology” Hair cortisol and cortisone levels increase with age, are higher in diabetics, vary by gender, decrease with frequent hair washing, and are lower in winter.
128 citations
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January 1996 in “Journal of analytical toxicology.” Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.
117 citations
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May 2017 in “Human Reproduction Update” The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.
71 citations
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July 2015 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.
56 citations
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January 1999 in “The Analyst” The method accurately measures certain steroids in human hair, showing different levels in males and females.
47 citations
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November 1966 in “Archives of Dermatology” Trichorrhexis nodosa is mainly caused by hair trauma, not a metabolic defect.
46 citations
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November 2014 in “The Journal of Clinical Endocrinology & Metabolism” Men with isolated hypogonadotropic hypogonadism have partial steroid deficiencies, while those with panhypopituitarism have severe deficiencies.
33 citations
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June 1995 in “International journal of legal medicine” Environmental factors can greatly reduce drug levels in hair.
31 citations
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January 2018 in “Pediatric annals” Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
30 citations
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March 2012 in “Journal of Analytical Toxicology” THCCOOH levels in hair decrease from root to tip and don't match well with self-reported cannabis use.
27 citations
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April 2013 in “Reviews in endocrine and metabolic disorders” The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
27 citations
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July 2001 in “Journal of Pharmaceutical and Biomedical Analysis” Finasteride remains stable for two years with proper storage.
22 citations
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September 2003 in “Journal of Investigative Dermatology” New mutations in the EBP gene cause CDPX2, affecting bones, skin, eyes, and hair, with females generally less affected than males.
21 citations
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November 2010 in “Talanta” Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.
20 citations
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August 2017 in “Drug testing and analysis” Drugs localize differently in hair strands based on their properties.
20 citations
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December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications” Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
16 citations
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February 2018 in “European Journal of Endocrinology” Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
15 citations
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October 2016 in “Steroids” Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
15 citations
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October 2010 in “Archives of Toxicology” A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.
14 citations
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May 2020 in “Drug Testing and Analysis” A new method was created to measure metformin in hair, showing potential for monitoring treatment and medical investigations.
14 citations
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January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
14 citations
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July 2017 in “Monatshefte für Chemie - Chemical Monthly” Analytical chemistry helps understand the makeup and use of ancient medicines, but it's complex and challenging.