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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Understanding different species' regeneration can improve mammalian healing.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Skin stem cells help repair damage and maintain healthy skin.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Stem cell self-renewal is complex and needs more research for full understanding.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.

Wnt/β-catenin signaling is crucial for cell fusion in placental development.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Muscles and nerves that cause goosebumps also help control hair growth.

Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Fibroblasts can be turned into melanocytes for potential skin treatments.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

Blocking IL-17 signaling may reduce skin inflammation and delay aging.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Researchers found 15 new genetic links to skin traits in Japanese women.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.