June 2020 in “Journal of Investigative Dermatology” The symposium highlighted the importance of genetics in understanding and treating complex skin diseases.
426 citations
,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
132 citations
,
August 2008 in “Development” Dlx3 is essential for hair growth and regeneration.
130 citations
,
December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle melanocytes die during hair regression.
127 citations
,
January 2008 in “PloS one” Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
114 citations
,
February 2023 in “International Journal of Molecular Sciences” The skin microbiome is crucial for skin health, and more research is needed to explore its role and potential treatments.
112 citations
,
September 2021 in “BMC Biology” Key genes and factors crucial for hair follicle development and wool traits in Merino sheep were identified.
98 citations
,
December 2015 in “The Journal of Cell Biology” Keratin is crucial for skin barrier formation and affects mitochondrial function.
83 citations
,
October 2012 in “International Journal of Oncology” Wedelolactone selectively kills prostate cancer cells without harming normal cells.
74 citations
,
January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
56 citations
,
January 2023 in “Genes & Diseases” Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
53 citations
,
October 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical calcitriol-analogs can reduce hair loss caused by chemotherapy.
44 citations
,
November 2022 in “Frontiers in Immunology” TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.
41 citations
,
December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
37 citations
,
February 2024 in “Military Medical Research” Biomaterials can help heal wounds without scars and regenerate skin features.
36 citations
,
January 2021 in “Frontiers in Cell and Developmental Biology” Hypoxia and epigenetics are crucial for cell growth and tissue regeneration.
36 citations
,
February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” The vitamin D receptor can work without its usual activating molecule.
30 citations
,
February 2023 in “Journal of Investigative Dermatology” OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.
23 citations
,
October 2009 in “Gastroenterology” Vitamin D is crucial for bone health and preventing serious diseases.
20 citations
,
September 2004 in “Journal of Anatomy” The inner root sheath evolved to help hair grow safely through the skin in mammals.
19 citations
,
December 2023 in “Journal of Investigative Dermatology” Scalp hair follicle microbes affect hair health and could be used for treatments.
19 citations
,
May 2016 in “Biology Direct” A new method, iSiMPRe, effectively identifies key protein regions in cancer genes, highlighting potential drug targets.
19 citations
,
March 2016 in “Frontiers in Plant Science” Spermidine is essential for plant growth and adaptation to stress.
18 citations
,
July 2024 in “Frontiers in Immunology” Targeting specific molecular pathways may improve treatments for chemoresistant cancers.
17 citations
,
May 2014 in “Cell transplantation” Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
16 citations
,
February 2022 in “Science Advances” Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
16 citations
,
September 2020 in “Animals” circRNA-1926 helps goat stem cells turn into hair follicles by affecting miR-148a/b-3p and CDK19.
11 citations
,
October 2021 in “Frontiers in Cell and Developmental Biology” Non-coding RNAs are important for hair growth and could lead to new hair loss treatments, but more research is needed.
9 citations
,
June 2024 in “BMC Genomics” Wool color in Gangba sheep is influenced by multiple genes and genetic mechanisms.
9 citations
,
July 2022 in “Cell reports” Sox2 controls hair color by affecting pigment production in hair follicles.