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GlossaryChromosome

long DNA molecule with part or all of genetic material

A chromosome is a long, thread-like structure made of DNA and proteins that carries genetic information. In humans, each cell typically contains 46 chromosomes, which are organized into 23 pairs. These structures are crucial for the proper distribution of genetic material during cell division and play a key role in heredity and the functioning of an organism.

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The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

research The human type I keratin gene family: Characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain

70 citations , December 2004 in “Differentiation”

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

research Toxicological Studies on Procyanidin B-2 for Extern?al Application as a Hair Growing Agent

30 citations , May 1999 in “Food and chemical toxicology”

Procyanidin B-2 is safe to use on skin as a hair growth product.

research Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition

14 citations , April 2019 in “Genes”

Researchers found a genetic region that influences the number of coat layers in dogs.

Patched-Associated Tumors: Modifier Genes and Pathogenesis

research Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese

February 2022

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

research The Shaven (Sha) Mutation, Chromosome 15

1 citations , August 2020

The Shaven mutation in mice affects hair growth and causes a greasy coat due to abnormal lipid content.

research Mapping of a novel locus for keratosis follicularis squamosa on chromosome 7p14.3–7p12.1

4 citations , September 2010 in “Journal of Dermatological Science”

A new gene location for Keratosis follicularis squamosa was found on chromosome 7p14.3-7p12.1.

research A locus on distal chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice

62 citations , April 2008 in “Neurobiology of aging”

Scientists found a gene in mice that causes early hearing loss.

research Prediction of male-pattern baldness from genotypes

37 citations , October 2015 in “European Journal of Human Genetics”

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

research Congenital Atrichia: A Case Report

September 2023 in “International journal of science and healthcare research”

Genetic testing is crucial for diagnosing congenital atrichia, a rare condition causing irreversible hair loss.

research An Australian family with macular dystrophy linked to autosomal recessive alopecia universalis

3 citations , February 2001 in “British journal of ophthalmology”

An Australian with rare hair loss and eye conditions had a gene linked to both, not seen together before.

research Identification of novel mutation in theHRgene responsible for atrichia with papular lesions in a Pakistani family

5 citations , September 2013 in “The Journal of Dermatology”

Researchers found a new mutation in the HR gene causing hair loss and skin bumps in a Pakistani family.

research Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases

January 2012 in “Faculty of Health; Institute of Health and Biomedical Innovation”

Early-onset hair loss is linked to Parkinson's disease and decreased fertility.

research Banded Scalp Hair with an Unusual Glistening Appearance in a Teenager: A Quiz

1 citations , January 2018 in “Acta dermato-venereologica”

A teenager's hair with alternating white and dark bands, known as Pili annulati, is a genetic condition that is usually harmless and often considered attractive.

research Cosmeceutical Treatments for Androgenetic Alopecia

August 2015

AGA is caused by genetics and androgens, treatable with finasteride and minoxidil.

research Autosomal recessive pure hair and nail ectodermal dysplasia linked to chromosome 12p11.1-q14.3 without KRTHB5 gene mutation

11 citations , July 2010 in “European Journal of Dermatology”

The condition is linked to chromosome 12, but no mutations were found in the known genes.

research Characterization of X-Linked SNP genotypic variation in globally distributed human populations

31 citations , January 2010 in “GenomeBiology.com (London. Print)”

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

Copy Number Variation Regions in Nellore Cattle: Evidence of Environmental Adaptation

research Copy number variation regions in Nellore cattle: Evidences of environment adaptation

21 citations , November 2017 in “Livestock science”

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Cloning of the Human Phenol Sulfotransferase Gene Family: Three Genes Implicated in the Metabolism of Catecholamines, Thyroid Hormones, and Drugs

research Cloning of the human phenol sulfotransferase gene family: three genes implicated in the metabolism of catecholamines, thyroid hormones and drugs

26 citations , February 1998 in “Chemico-Biological Interactions”

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

research FOXN1 Duplication and Congenital Hypertrichosis

3 citations , March 2017 in “Pediatric Dermatology”

FOXN1 duplication can cause excessive hair growth.

research Lithium alters mitotic progression in stamen hair cells of Tradescantia in a time-dependent and reversible fashion.

28 citations , October 1987 in “PubMed”

Lithium temporarily stops cell division in plant cells, but this can be reversed with certain chemicals.

research Index of Suspicion

2 citations , May 2007 in “Pediatrics in Review”

Thorough history and examination are crucial for diagnosing genetic disorders like juvenile polyposis and hypomelanosis of Ito.

research Primary Amenorrhoea

April 2024 in “International Journal of Advanced Multidisciplinary Research and Studies”

Early investigation and a team approach are crucial for managing primary amenorrhea effectively.

research THE PATHOGENESIS OF ALOPECIA AREATA

89 citations , October 1996 in “Dermatologic Clinics”

Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.

research Characterization of a Cluster of Human High/Ultrahigh Sulfur Keratin-associated Protein Genes Embedded in the Type I Keratin Gene Domain on Chromosome 17q12-21

98 citations , June 2001 in “Journal of biological chemistry/The Journal of biological chemistry”

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

research Insertional mutation of the hairless locus on mouse Chromosome 14

19 citations , November 1993 in “Mammalian Genome”

A gene mutation in mice causes permanent hair loss and skin issues.

research Genome-wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26

62 citations , March 2008 in “American Journal of Human Genetics”

Hair loss gene found on chromosome 3q26.

Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 21 in Fond Memory of Dr. Peter Steinert

research Hair Keratin Associated Proteins: Characterization of a Second High Sulfur KAP Gene Domain on Human Chromosome 2111In fond memory of Dr Peter Steinert.

62 citations , January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.