16 citations
,
March 2024 in “International Journal of Molecular Sciences” Natural compounds and biomimetic engineering can improve wound healing by enhancing fibroblast activity.
16 citations
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April 2021 in “Biomedicines” Ferulic acid helps wounds heal faster by reducing inflammation and promoting skin cell movement.
15 citations
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March 2021 in “EMBO Reports” PRSS35 enzyme may help start skin tumors and could be a target for cancer treatment.
15 citations
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March 2012 in “International journal of nanomedicine” Local injections of nanosized rhEPO can speed up skin healing and improve quality after deep second-degree burns.
14 citations
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January 2008 in “Dermatology” Vitamin D made by the skin plays a role in immune defense and skin health, and more research is needed to understand its full effects.
10 citations
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July 2025 in “Stem Cell Research & Therapy” Engineering strategies improve stem cells' ability to heal wounds effectively.
10 citations
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July 2023 in “Pharmaceutics” Activating PKM2 and Wnt/β-catenin signaling speeds up wound healing.
10 citations
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July 2019 in “Advances in Wound Care” Reducing Flightless I protein improves wound healing by activating skin stem cells.
10 citations
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January 2018 in “Elsevier eBooks” Burn scars heal abnormally and more research is needed to find better treatments.
9 citations
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July 2022 in “British Journal of Pharmacology” Blocking the mineralocorticoid receptor improves wound healing by reducing inflammation and promoting blood vessel growth.
9 citations
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July 2018 in “Current Pharmaceutical Design” HO-1 helps skin health and healing but can worsen melanoma; it's a potential treatment target for skin diseases.
8 citations
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November 2023 in “Frontiers in Bioengineering and Biotechnology” Combining metals and herbs in microneedles can improve wound healing.
8 citations
,
February 2023 in “American Journal of Physiology-Cell Physiology” Adiponectin and bradykinin play important roles in skin health and may help treat skin conditions.
7 citations
,
May 2018 in “Indian Journal of Pharmacology” Algerian Carthamus caeruleus L plant has anti-inflammatory properties, heals wounds effectively, and may help with hair growth.
6 citations
,
July 2023 in “Plants” Datura metel leaf extracts help heal wounds effectively.
6 citations
,
November 2022 in “Journal of Tissue Engineering and Regenerative Medicine” Zebularine improved skin structure but delayed wound healing in diabetic mice.
6 citations
,
June 2022 in “Frontiers in Bioengineering and Biotechnology” The gel with icariin speeds up wound healing, reduces scarring, and helps hair growth by controlling BMP4 signaling. It also reduces inflammation and improves wound quality in mice, adapts to different wound shapes, and gradually releases icariin to aid healing. It also prevents too much collagen and myofibroblast formation during skin healing.
4 citations
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September 2025 in “Pharmaceutics” Natural hydrogels can improve wound healing but face challenges in becoming widely used in clinics.
4 citations
,
January 2025 in “Frontiers in Pharmacology” Multiomics helps understand and improve skin healing and repair.
3 citations
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July 2024 in “Cell Proliferation” Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.
3 citations
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March 2024 in “Viruses” γδ T cells are essential for wound healing after poxvirus infection.
3 citations
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November 2021 in “Journal of biomedical materials research. Part B, Applied biomaterials” AMFIBHA scaffold significantly healed large full-thickness burn wounds in rabbits and restored skin's mechanical properties.
3 citations
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January 2012 in “Elsevier eBooks” Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.
2 citations
,
October 2025 in “Chinese Medicine” Berberine delivery systems improve wound healing by enhancing bioavailability, reducing inflammation, and promoting tissue regeneration.
2 citations
,
July 2025 in “Cells” Platelet lysate is better than fetal bovine serum for growing stem cells and healing wounds.
2 citations
,
July 2025 in “Chemical Engineering Journal” The hydrogel dressing effectively treats infected wounds by combining infection control and tissue regeneration.
2 citations
,
February 2024 in “International Journal of Molecular Sciences” Negative Pressure Wound Therapy speeds up wound healing by reducing inflammation and promoting skin cell growth.
2 citations
,
December 2023 in “Advanced science” Glycosaminoglycans help heal wounds but aren't yet ready for clinical use.
2 citations
,
May 2023 in “Frontiers in immunology” Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.
2 citations
,
May 2023 in “Frontiers in Bioengineering and Biotechnology” The document concludes that more research is needed on making and understanding biomaterial scaffolds for wound healing.