research 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH
Methylation of the 5-AR2 gene may cause resistance to Finasteride in BPH patients.
Search
for
Sort by
Research
690-720 / 1000+ results
research Cyproterone Acetate: A Genotoxic Carcinogen?
Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.
research Polymeric nanoparticles-embedded organogel for roxithromycin delivery to hair follicles
Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
research COVID-19: How Effective Are the Repurposed Drugs and Novel Agents in Treating the Infection?
Vaccination is the most effective way to reduce COVID-19 transmission.
research Acute and 30-day oral toxicity studies of a novel coccidiostat – ethanamizuril
Ethanamizuril is safe for rats at 20 mg/kg feed, but higher doses cause hair loss, organ changes, and liver, kidney, and lung damage.
research Finasteride < Rec INN; BAN; USAN >
research Re: Inhibitors of 5α-Reductase-Related Side Effects in Patients Seeking Medical Care for Sexual Dysfunction
research TICE salvage chemotherapy treats germ-cell tumors effectively
TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.
research Finasteride may increase risk of seizures
research Cyproteronacetat zur topischen Therapie androgenabhängiger Erkrankungen
Cyproterone acetate is used for topical treatment of diseases dependent on male hormones.
research Evaluating the safety profile of α-1 blockers, 5α-reductase inhibitors, and PDE5I for BPH: a disproportionality analysis of real-world adverse events based on FDA adverse event reporting system (FAERS)
These medications for BPH have known risks and may have new side effects.
research Limits of Visual Detection for Finasteride Polymorphs in Prepared Binary Mixtures: Analysis by X‐ray Powder Diffraction
research Proliferative and necrotizing otitis externa in four cats
Topical 0.1% tacrolimus significantly improved ear infections in cats.
research Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research [Retracted] Mechanism of Anti‐Inflammatory Drugs in the Early Treatment of Oral Gingival Mucosa and Soft Tissue Trauma
Levofloxacin and metronidazole reduce inflammation and speed up healing in gingival wounds.
research Case Report. Kerion Celsi effectively treated with terbinafine. Characteristics of kerion Celsi in the elderly in Japan
A man in Japan got better from a scalp fungal infection using terbinafine.
research Veterinary Pharmacology
Some plant extracts may treat livestock diseases, certain animal treatments are safe and effective, but more research on drug safety and resistance is needed.
research A Novel 3D Printed Model of Infected Human Hair Follicles to Demonstrate Targeted Delivery of Nanoantibiotics
Nanoencapsulated antibiotics are more effective in treating hair follicle infections than free antibiotics.
research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase
New compounds called benzoquinolinones may treat conditions linked to excess DHT.
research [Prophylaxis of recurring low-flow priapism : Experimental botulinum neurotoxin injection into the ischiocavernosus muscle].
Botulinum neurotoxin injections into the pelvic muscles successfully prevented priapism relapse for over six months.
research Testosterone regulates levels of cystic fibrosis transmembrane regulator, adenylate cyclase, and cAMP in the seminal vesicles of orchidectomized rats
Testosterone boosts fluid and electrolyte secretion in seminal vesicles, aiding sperm function.
research The study of preventing floppy iris syndrome during age-related cataract surgery
Atropine and neosynephrine effectively prevent floppy iris syndrome during cataract surgery.
research Chemical Mechanism of the Covalent Modification of 5.alpha.-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects
Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
research Finasteride-related sexual and neuropsychiatric AEs
research Anticancer drugs in surface waters
Anticancer drugs are increasingly found in surface waters, and their long-term environmental effects are not well understood, requiring better testing methods.
research Protein degradation: expanding the toolbox to restrain cancer drug resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Multifunctional Dynamic Cerium-Polypeptide Hydrogel with Antibacterial Antioxidative Antiinflammatory for Multidrug-Resistant Bacterial Infected Wound Healing
The cerium-polypeptide hydrogel effectively heals drug-resistant bacterial wounds by fighting bacteria, reducing inflammation, and promoting tissue repair.
research Systemic Antifungals
Terbinafine is the most effective medicine for fungal nail infections, especially for diabetics and those with weak immune systems.
research Clinical effectiveness of ethinylestradiol-cyproterone acetate and raloxifene combination therapy in polycystic ovary syndrome-associated infertility
The combination therapy effectively treats infertility in PCOS without major side effects.
research Bacteriological study of Acne Vulgaris in Cairo Egypt
The conclusion is that antibiotics are not the best acne treatment and early treatment is important to prevent scarring, especially for those with a family history of acne.