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Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.

Notch signaling is crucial for specifying niche cells in Drosophila testis.

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

KAP6 genes are conserved across species and active in hair follicles.

The new model helps understand and develop treatments for genetic skin disorders like AEC.

cDermo-1 causes dense skin, feathers, and scales in chickens.

A defective gene causes hair loss and taste insensitivity in BTBR mice.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

ILC1-like cells can cause alopecia areata by themselves.

KRT14 gene variants cause dermatopathia pigmentosa reticularis, affecting nails, teeth, and hair.

Aire mutation reduces alopecia areata, while Notch4 mutation prevents it in mice.

Overexpressing PKCα in mice skin increases inflammation but doesn't affect tumor growth.

The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Human hair keratin genes hHa2 and hHb1 are located on chromosomes 17 and 12.

Sonic hedgehog signaling is needed for the development of touch-receptor cells in the skin, and the loss of Polycomb repressive complex 2 can lead to more of these cells.

Cucurbitacin helps mice grow hair by blocking a protein that stops hair growth.

KIT's role in skin cells is not entirely independent, as other cells can influence its function.

An 8-year-old girl has a rare, irreversible hair loss condition caused by a genetic mutation.

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Type XVII collagen helps control skin cell growth and may have anti-aging effects.

Significant progress was made in understanding PXE, but effective treatments are still needed.

N-WASP is essential for healthy skin and preventing inflammation.

Csdc2 helps hair growth in cashmere goats by regulating specific genes.

PCR genotyping in cre-loxP mice can be inaccurate due to unintended gene deletions in non-target tissues.

MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

α- and γ-catenins help develop fetal skin by 23 weeks.