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research Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b

101 citations , August 2001 in “The Journal of Cell Biology”

A new keratin 6 type in mice explains why some mice without certain keratin genes still have normal hair and nails.

research CRISPR/Cas9-Mediated Generation of COL7A1-Deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa.

2 citations , October 2023 in “PubMed”

Scientists created a cell model to study and find treatments for a skin disease called RDEB.

research Single nucleotide polymorphisms in the KRT82 promoter region modulate irregular thickening and patchiness in the dorsal skin of New Zealand rabbits

2 citations , May 2024 in “BMC Genomics”

Certain genetic changes in the KRT82 gene may cause patchy skin in New Zealand rabbits.

Characteristics of KRT80 and Its Roles in Neoplastic Diseases

research Characters of KRT80 and its roles in neoplasms diseases

2 citations , May 2023 in “Cancer medicine”

KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.

research Crosslinking Between Trichocyte Keratins and Keratin Associated Proteins

13 citations , January 2018 in “Advances in experimental medicine and biology”

research Loss of Keratin K2 Expression Causes Aberrant Aggregation of K10, Hyperkeratosis, and Inflammation

32 citations , April 2014 in “The journal of investigative dermatology/Journal of investigative dermatology”

Loss of keratin K2 causes skin problems and inflammation.

research P7 p63, K14 and p53 expression in epithelial layers of tumor-distant oral mucosa in patients with oral squamous cell carcinoma

March 2010 in “European Journal of Cancer Supplements”

research Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice

15 citations , May 2014 in “Journal of Biological Chemistry”

A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.

Chromatin Architectural Protein CTCF Controls Epidermal Barrier Formation, Hair Follicle Fate Maintenance, and Suppresses Inflammatory Responses in the Skin Epithelium

research 874 Chromatin architectural protein CTCF controls epidermal barrier formation, hair follicle fate maintenance and suppresses inflammatory responses in the skin epithelium

April 2017 in “Journal of Investigative Dermatology”

The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.

research Pvalb8, a Type of Oncomodulin, Regulates Neuromast Development and Auditory Function in Zebrafish

October 2025 in “Cells”

Pvalb8 is essential for zebrafish hearing and hair cell development, and its mutation causes hearing loss.

research CD98hc (SLC3A2) regulation of skin homeostasis wanes with age

35 citations , January 2013 in “The Journal of experimental medicine/The journal of experimental medicine”

CD98hc's role in skin health decreases with age.

research Overexpression of human keratin 16 produces a distinct skin phenotype in transgenic mouse skin

25 citations , September 1995 in “Biochemistry and Cell Biology”

High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.

research CRISPR/Cas9-mediated Generation ofCOL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa

June 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Scientists created cell lines to study a genetic skin disorder using CRISPR technology.

research Glypican-1, -4 and 6 Participate in the Hair Follicle Stem Cell Differentiation via Specific Interactions with BMP2R, Fz7 and Patched 1

October 2024 in “SPIRE - Sciences Po Institutional REpository”

research Close Shave for a Keratin Disorder—K6hf Polymorphism Linked to Pseudofolliculitis Barbae

12 citations , March 2004 in “Journal of Investigative Dermatology”

research Fine Mapping and Identifying the Mutation Gene of snthr -1Bao ScantHair Mouse

July 2009 in “TSpace”

The scant hair in snthr-1Bao mice is likely caused by a deletion affecting the Plcd1 gene.

research Cytokeratin 7 and 20

1 citations , February 2012 in “InTech eBooks”

CK7 and CK20 help identify and classify tumors for accurate cancer diagnosis.

research P5 Assembly of hair keratins in thansfected cultured cells

April 1996 in “Journal of Dermatological Science”

research The Region Coding for the Helix Termination Motif and the Adjacent Intron 6 of the Human Type I Hair Keratin Gene hHa2 Contains Three Natural, Closely Spaced Polymorphic Sites

6 citations , March 1996 in “Journal of Investigative Dermatology”

research Identification of llama KRTAP7-1 and KRTAP8-1 fiber genes and polymorphism screening

2 citations , May 2019 in “Small ruminant research”

Mutations in specific llama genes may affect fiber quality for textiles.

research Hair Defects and Pup Loss in Mice with Targeted Deletion of the First Cut Repeat Domain of theCux/CDPHomeoprotein Gene

48 citations , August 1998 in “Developmental Biology”

Deleting part of a gene in mice causes wavy hair and high pup loss.

research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene

January 2024 in “Animals”

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

research Isolation and Characterization of a Putative Keratin-Associated Protein Gene Expressed in Embryonic Skin of Mice

22 citations , July 1998 in “Journal of Investigative Dermatology”

The 4C32 gene may help in mouse skin development and differentiation.

research Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues.

57 citations , January 1987 in “Journal of Biological Chemistry”

Different keratins have unique expression patterns in mouse skin cells.

research KRT72 wt Allele

February 2020 in “Definitions”

KRT72 gene helps form hair.

research CCN2 modulates hair follicle cycling in mice

21 citations , October 2013 in “Molecular Biology of the Cell”

The protein CCN2 controls hair growth by affecting hair follicle formation and stem cell activity in mice.

research Genetic Ablation of the CDP/Cux Protein C Terminus Results in Hair Cycle Defects and Reduced Male Fertility

97 citations , March 2002 in “Molecular and cellular biology”

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

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