research LB1154 Rising antimicrobial resistance in chronic wounds
DACC-based dressings are more effective than silver-based ones for treating chronic wounds with antimicrobial resistance.
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research Compounded topical preparations in plaque psoriasis: Still a place for it in 2018?
Compounded topical preparations should be used with caution for severe psoriasis and generally come after systemic treatments.
research Effective treatment of folliculitis decalvans using selected antimicrobial agents
Antimicrobial therapy can help manage Folliculitis Decalvans.
research Follicular-targeted delivery of spironolactone provided by polymeric nanoparticles
Nanoparticles can effectively deliver spironolactone to hair follicles for treating alopecia and acne.
research Highly solubilized and skin-permeable finasteride formulation using HPCD-incorporated chitosan nanocapsules to promote hair regeneration
A new topical finasteride formulation effectively promotes hair growth with fewer side effects.
research Cell-repellent polyampholyte for conformal coating on microstructures
Prevelex, a polyampholyte, can create a cell-repellent coating on microdevices, which can be useful in biomedical applications like hair follicle regeneration.
research A case of treatment-resistant erosive pustular dermatosis of the scalp
Combination therapy may be more effective for difficult-to-treat scalp conditions.
research 308-nm Excimer Lamp vs. Combination of 308-nm Excimer Lamp and 10% Liquor Carbonis Detergens in Patients With Scalp Psoriasis: A Randomized, Single-Blinded, Controlled Trial
The combination of the excimer lamp and liquor carbonis detergens is more effective for scalp psoriasis than the lamp alone.
research Normal-pressure-prepared chitosan carbonate liquid dressing: Spontaneous transformation into a pure chitosan water-resistant film and enhanced wound repair
The new chitosan dressing heals wounds better and faster than current products.
research Botanical Lotion CG428
Botanical lotion CG428 may help regrow hair and reduce scalp inflammation in chemotherapy patients.
research Comparative Study between The Efficacy and Safety of Topical Immune Therapy with Diphenylcyclopropenone versus Anthralin in The Treatment of Resistant Alopecia Areata
Diphenylcyclopropenone (DPCP) is more effective than anthralin for treating resistant alopecia areata.
research Lysine Carboxymethyl Cysteinate (LCC) Protects the Epidermis from UVB-Induced Barrier Damage Through the Activation of Autophagy
Lysine carboxymethyl cysteinate (LCC) has been shown to protect the epidermis from UVB-induced damage by activating autophagy. In a study using a 3D living skin equivalent model, LCC restored epidermal cell thickness by 9.67% and significantly increased the expression of biomarkers related to skin hydration and cornified envelope formation. Transcriptomics analysis in human keratinocytes revealed that LCC influences glutathione synthesis, oxidation response, inflammation, and autophagy. The protective effects of LCC, particularly in barrier formation and autophagy, were confirmed and shown to be negated by chloroquine, an autophagy inhibitor. These findings highlight LCC's potential in safeguarding skin integrity against UVB damage.
research Impact of Cyproterone Acetate and Ethinylestradiol on Clomiphene Resistant PCOS Patient with High Serum AMH level
Cyproterone acetate and ethinylestradiol significantly lowered AMH levels in PCOS patients resistant to clomiphene.
research Allergic and irritant contact dermatitis compared in the treatment of alopecia totalis and universalis. A comparison of the value of topical diphencyprone and tretinoin gel
DPCP is more effective than tretinoin gel for treating severe alopecia.
research 709 Nitric oxide-releasing topical therapeutic agent for atopic dermatitis
SB414 may be an effective treatment for atopic dermatitis by reducing swelling and bacterial infection.
research Keratin hydrogels support the sustained release of bioactive ciprofloxacin
Keratin hydrogels can slowly release effective ciprofloxacin to prevent infections.
research PEMANFAATAN LIMBAH KULIT BUAH SALAK PONDOH (Salaccae edulis Reinw) MENJADI SEDIAAN SAMPO DAN AKTIVITASNYA TERHADAP Staphylococcus epidermidis DAN Candida albicans
Pondoh salak fruit peel extract is effective in shampoo and has strong antimicrobial properties.
research A systematic review of tumor necrosis factor-α blockers, anti-interleukins, and small molecule inhibitors for dissecting cellulitis of the scalp treatment
TNF-α blockers and IL inhibitors improve symptoms in most patients with severe scalp condition, but more research is needed.
research Effects of an oral contraceptive containing chlormadinone acetate and ethinylestradiol on hair and skin quality in women wishing to use hormonal contraception
The oral contraceptive improved hair and skin quality in women.
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
research Dissecting cellulitis of the scalp successfully treated with infliximab
Infliximab was effective in treating a scalp condition that did not respond to other treatments.
research The effect of polyphloretin phosphate, polyoestradiol phosphate, a diphosphonate and a polyphosphate on calcification induced by dihydrotachysterol in skin, aorta and kidney of rats
The diphosphonate was the most effective at preventing calcification in rats.
research A rare case of coinfection with white piedra and pediculosis capitis
A woman had a rare infection of both white piedra and head lice, which improved after 10 weeks of antifungal treatment.
research Treatment of Subacute and Chronic Discoid Lupus Erythematosus with Intensive Calcium Pantothenate Therapy11From the Hair Laboratory of the Department of Dermatology and Syphilology of the College of Medicine, University of Cincinnati.
Calcium pantothenate therapy improved symptoms of discoid lupus erythematosus without side effects.
research Topical Immunotherapy with Diphenylcyclopropenone in Paediatric Patients with Alopecia Areata—A Retrospective Study of 97 Patients
Topical immunotherapy with DPCP led to some hair regrowth in most pediatric alopecia areata patients, especially those with milder cases and longer treatment.
research Commentary: Treatment of lichen planopilaris
Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.
research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen
In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.
research The Novel Excipient, Dodecyl-2-N, N-dimethylaminopropionate Hydrochloride (DDAIP-HCl) Improves the Flux of Minoxidil in Human Skin
DDAIP-HCl significantly increases minoxidil absorption into the skin.
research Treatment of hirsutism and acne in women with two combinations of cyproterone acetate and ethinylestradiol.
Cyproterone acetate and ethinylestradiol effectively reduce hirsutism and acne in women.
research [Advances in topical therapy of skin diseases (author's transl)].
New treatments for skin diseases in 1979 showed promising results with fewer side effects.