research A computational modelling framework to quantify the effects of passaging cell lines
Cell characteristics change with passage numbers, affecting experiment results.
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research Isolation of Mouse Hair Follicle Bulge Stem Cells and Their Functional Analysis in a Reconstitution Assay
Mouse hair follicle stem cells were successfully isolated and used to regenerate hair follicles with two different methods.
research Decision letter: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
research An in vivo method for the detection of somatic mutations at the cellular level in mice
A new method can detect mutations in mice by observing changes in hair follicle cells.
research Clonal multipotency and effect of long-term in vitro expansion on differentiation potential of human hair follicle derived mesenchymal stem cells
Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
research Gfp-Expressing Vascularization of Gelfoam® as a Rapid in Vivo Assay of Angiogenesis Stimulators and Inhibitors
The assay quickly identifies substances that increase or decrease blood vessel growth.
research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse
A new method helps grow skin cells from humans and mice more easily and quickly.
research Cloning and Characterization of a Mouse Type I Hair Keratin cDNA
research A computational modelling framework to quantify the effects of passaging cell lines
Passage numbers affect cell growth and experiment results.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single‐cell RNA ‐sequencing
Different types of resting melanocyte stem cells have unique characteristics and vary in their potential to become other cells.
research In vivo monitoring of survival and proliferation of hair stem cells in hair follicle regeneration animal model
Hair stem cells were tracked in mice using a special imaging technique, showing that it's possible to monitor hair growth this way.
research Use of primary keratinocyte cultures from plucked human hairs for analysis of gap junctional intercellular communication
Hair follicle cultures are effective for studying cell communication and testing chemicals.
research Two novel CreERT2 transgenic mouse lines to study melanocytic cells in vivo
New mouse models help study melanocytic cells for melanoma research.
research Nonviral in Situ Green Fluorescent Protein Labeling and Culture of Primary, Adult Human Hair Follicle Epithelial Progenitor Cells
A nonviral method was developed to label and culture human hair follicle stem cells.
research Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts
The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
research Non-small cell lung carcinoma spheroid models in agarose microwells for drug response studies
The platform effectively grows lung cancer cell spheroids for drug testing.
research Demonstration of early anagen-specific stimulatory factors within skin tissue for in vitro mesenchymal-epithelial interaction in collagen embedded hair follicle mixed culture
research Single-cell analysis of temporal immune cell dynamics in alopecia areata reveals a causal role for clonally expanded CD8+ T cells in disease
Clonally expanded CD8+ T cells cause alopecia areata.
research Live-cell Imaging and Analysis of Germline Stem Cell Mitosis in Caenorhabditis elegans
The protocol allows easy imaging of dividing cells in C. elegans and can be used for other organisms.
research Follicular cell implantation: an update on “hair follicle cloning”
The document concludes that while "hair follicle cloning" shows promise for unlimited donor hair, it faces challenges with consistency and safety in humans.
research Selection of adult hair follicle stem cells and the effects of #beta#--catenin
A method was found to select hair follicle stem cells, and beta-catenin helps them grow and change.
research Histocultures and Their Use
Histocultures help personalize cancer treatments, study hair growth, and explore immune responses.
research Differential metabolic adaptations define responses of winner and loser oncogenic mutant stem cells in skin epidermisin vivo
Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.
research Author response: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
research K6/ODC transgenic mice as a sensitive model for carcinogen identification
K6/ODC transgenic mice are effective for quickly identifying cancer-causing chemicals.
research In Vitro Culturing and Harvesting of Human Plucked Hair Follicles
Growing hair cells in the lab from plucked hairs could lead to a new, less invasive, and cheaper baldness treatment.
research Functional analysis of thymosin beta-4 using over-expressing transgenic mice
Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.
research Skin toxicity determined in vitro by three-dimensional, native-state histoculture.
This model can replace animal testing for quick, cost-effective skin toxicity tests.
research L-Ornithine ketoacid-transaminase assay in hair roots of homozygotes and heterozygotes for gyrate atrophy
research Characterization and quantification of wound-induced hair follicle neogenesis using in vivo confocal scanning laser microscopy
In vivo confocal scanning laser microscopy is an effective, non-invasive way to study and measure new hair growth after skin injury in mice.