research 231 Novel protocol for the invitro maintenance and expansion of adult epidermal LGR5+ stem cells
A new method helps grow skin stem cells better, which could improve skin grafts for burn victims.
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480-510 / 1000+ resultsresearch Visualization of individual cell division history in complex tissues
The tool iCOUNT helps understand how stem cells divide and affect tissue development and repair.
research Differential metabolic adaptations define responses of winner and loser oncogenic mutant stem cells in skin epidermisin vivo
Mutant stem cells adapt their metabolism differently to outcompete normal cells in the skin.
research The Majority of Multipotent Epidermal Stem Cells Do Not Protect Their Genome by Asymmetrical Chromosome Segregation
Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
research A computational modelling framework to quantify the effects of passaging cell lines
Cell characteristics change with passage numbers, affecting experiment results.
research A computational modelling framework to quantify the effects of passaging cell lines
Passage numbers affect cell growth and experiment results.
research Genetic Fate Mapping Using Site-Specific Recombinases
The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.
research Author response: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
research Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming
Long-term skin biopsy cultures can produce many fibroblasts that remain functional and can be reprogrammed.
research Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro
Mouse skin cells can become sperm-like cells in the lab.
research Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and multilineage differentiation through nuclear-cytoplasmic labeling
Transplanted bone marrow cells actively move, form clusters, and grow after transplantation.
research Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures
Human skin cells can be turned into versatile stem cells, but their ability to do so decreases with repeated use.
research Establishment and identification of immortalized sheep ovarian granulosa cells
A stable sheep ovarian cell line was created for studying reproduction and hormones.
research 1390 Lineage-committed fibroblast populations are more efficient at regenerating hair follicles in chamber grafting assays when compared to undifferentiated embryonic fibroblasts
Differentiated fibroblasts regenerate hair follicles better than undifferentiated ones.
research LB1606 Retainability of pluripotency and viability of multilineage-differentiating stress enduring (Muse) cells after repeated cryopreservation.
Muse cells keep their special features and can become different cell types even after being frozen and thawed three times.
research Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts
The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
research Hair follicle stem cell cultures reveal self‐organizing plasticity of stem cells and their progeny
The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse
A new method helps grow skin cells from humans and mice more easily and quickly.
research Manipulation of stem cell proliferation and lineage commitment:visualisation of label-retaining cells in wholemounts of mouse epidermis
Stem cell behavior varies with stimuli, and lineage changes can happen without affecting stem cell division.
research Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning
Human hair follicles can be used to create stem cells that might help clone hair for treating hair loss or helping burn patients.
research The Evolution of the Promise of Hair Cloning: How Hair Cell Cloning Will Fit Into Your Practice
Hair cell cloning could potentially rejuvenate shrinking hair follicles, allowing for lifelong hair maintenance.
research Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing
Different types of inactive melanocyte stem cells exist with unique characteristics and potential to develop into other cells.
research Functional analysis of thymosin beta-4 using over-expressing transgenic mice
Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.
research Selection of adult hair follicle stem cells and the effects of #beta#--catenin
A method was found to select hair follicle stem cells, and beta-catenin helps them grow and change.
research Distinct stem cells contribute to mammary gland development and maintenance
Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
research Notes from the Editor Emeritus
Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
research The River of Stem Cells
The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.
research Plasticity of differentiated cells in wound repair and tumorigenesis, part II: skin and intestine
Mature cells can re-enter the cell cycle and potentially lead to cancer.
research Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo
ING5 is crucial for stem cell maintenance and preventing certain cancers.
research Peer Review #1 of "Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning (v0.1)"
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.