research Next generation human skin constructs as advanced tools for drug development
Advanced human skin models improve drug development and could replace animal testing.
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research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results
Both mouse and rat models are effective for testing alopecia areata treatments.
research Pattern Hair Loss in Men
Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
research Nanoparticles in wound healing from hope to promise from promise to routine
Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.
research Thyroid hormone action on skin
Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
research Characterization of Hair Follicle Development in Engineered Skin Substitutes
Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
research Hair Follicle Regeneration in Skin Grafts: Current Concepts and Future Perspectives
Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
research Incisional Slit Grafting
Incisional slit grafting for hair transplantation gives natural-looking results and has a high success rate.
research Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research Optimization of menthol-loaded nanocapsules for skin application using the response surface methodology
Researchers created better skin-application menthol capsules that are stable, safe, and penetrate the skin quickly.
research Epidermal keratinocyte stem cells: their maintenance and regulation
Skin stem cells are maintained by signals from nearby cells and vary in their ability to renew and mature.
research Thyroid hormone action on skin.
Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.
research Dihydrotestosterone-induced hair regrowth inhibition by activating androgen receptor in C57BL6 mice simulates androgenetic alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Autologous cell–based therapy for male and female pattern hair loss using dermal sheath cup cells: A randomized placebo-controlled double-blinded dose-finding clinical study
DSC cell injections significantly improved hair density and diameter, showing potential as a hair loss treatment.
research Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration
Fat stem cell particles help regrow hair.
research In vitro skin models to study epithelial regeneration from the hair follicle
PSU are better than THF at regenerating skin layers in lab models.
research Accelerated senescence in skin in a murine model of radiation-induced multi-organ injury
High-dose radiation speeds up aging in skin stem cells.
research Systematic review of the therapeutic roles of adipose tissue in dermatology
Fat tissue treatments may help with wound healing and hair growth, but more research with larger groups is needed to be sure.
research The effect of plasma rich in growth factors combined with follicular unit extraction surgery for the treatment of hair loss: A pilot study
Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.
research Hair Repair Surgery
Corrective hair repair surgery can significantly improve appearance and quality of life for patients with unsatisfactory results from old hair transplants.
research Induction of hair follicle neogenesis with cultured mouse dermal papilla cells in de novo regenerated skin tissues
Scientists successfully grew new hair follicles in regenerated mouse skin using mouse and human cells.
research Hair Transplantation in Females
Hair transplantation is a viable treatment for some types of female hair loss, with careful donor assessment and attention to psychological factors.
research Considerations on Hair Research and Hair Growth
The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.
research Synergistic Wound Healing: Unraveling the Multi-Target Effects of Traditional Chinese Medicine and Its Biomaterials on Chronic Wound Pathways
Traditional Chinese Medicine and biomaterials help heal chronic wounds by targeting multiple pathways.
research Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair loss
Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.
research Scalp Lifting
Scalp lifting surgery can safely and effectively reduce baldness if done with careful planning and proper technique.
research Commentary on a Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia
PRP treatment increased hair density, especially in men and younger patients with AGA.
research Alternative synthesis of the anti-baldness compound RU58841
A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.
research Hair growth-promoting effect of recombinant human sonic hedgehog proteins
Sonic hedgehog proteins may help grow hair.