research Calcium blockers protect against sensory epithelial damage and hearing loss in Cx26-cKO mice
Calcium blockers may help prevent hearing loss by protecting hair cells.
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research Aging Alters Hair Cell Physiological Properties in Mice with Late-Onset Age-Related Hearing Loss.
Aging reduces hair cell size and function in mice, contributing to hearing loss.
research Les nouvelles stratégies thérapeutiques du traumatisme sonore par bruit d'arme chez le cobaye
Magnesium and caspase inhibitors help protect hearing after gunshot noise.
research Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia
Birds can regenerate inner ear cells using specific gene pathways, unlike mammals.
research CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
research CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells
CaBP1 and CaBP2 are necessary for proper hearing and neurotransmission in the ear's inner hair cells.
research Molecular basis of hair cell loss
The document concludes that there are no effective clinical treatments for hearing loss due to hair cell damage, but research is ongoing.
research Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear
Stem cell therapy could help regenerate inner ear hair cells to treat hearing loss.
research Autophagy-related protein 12 associates with anti-apoptotic B cell lymphoma-2 to promote apoptosis in gentamicin-induced inner ear hair cell loss
Blocking autophagy increases survival of inner ear hair cells exposed to gentamicin.
research Regulation of Tmem30b-mediated apical membrane homeostasis in auditory outer hair cells is critical for hearing
Tmem30b is essential for hearing by maintaining hair cell structure in the ear.
research Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research
Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.
research Dysregulation of Grainyhead-like 3 expression causes widespread developmental defects
Not having enough or having too much of the protein Grainyhead-like 3 leads to various developmental problems.
research Ototoxicity of Common Topical Antimycotic Preparations
Clotrimazole, miconazole, and tolnaftate are likely safe, but gentian violet is risky.
research The role of cochlea extracellular matrix in age related hearing loss
Changes in the cochlea's extracellular matrix contribute to age-related hearing loss.
research PŁYNY- NIE ZA DUŻO, NIE ZA MAŁO, LECZ W SAM RAZ
AI and new therapies show promise in medicine, especially for cancer and regenerative treatments.
research Histopathological change of age-related hearing loss in female advance-aged CBA/CaJ mice
Age-related hearing loss involves cochlear damage and metabolic changes.
research Folate Supplementation and Age-Related Hearing Loss
Folic acid might help with age-related hearing loss.
research Cancer vaccine strategies and studies of human thioredoxin reductase splice variants
Vaccines and targeting TrxR variants can help prevent cancer and reduce metastasis.
research Vestibular Hair Cell Regeneration and Restoration of Balance Function Induced by Math1 Gene Transfer
Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.
research Hair cell toxicology: With the help of a little fish
Zebrafish larvae are used to study and find treatments for ear cell damage because they are easier to observe and test than mammals.
research Hair cell loss – cause or consequence of hearing loss?
Hair cell loss usually happens after hearing loss starts.
research Natural Bizbenzoquinoline Derivatives Protect Zebrafish Lateral Line Sensory Hair Cells from Aminoglycoside Toxicity
Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.
research Influence of Myosin Regulatory Light Chain and Myosin Light Chain Kinase on the Physiological Function of Inner Ear Hair Cells
NM2 and RLC phosphorylation are essential for normal inner ear hair cell function.
research Experimental Studies of Inner Ear Hair Cell Regeneration.
Birds can regenerate inner ear hair cells from supporting cells, and mammals show potential for similar regeneration.
research Multimodal imaging of hair follicle bulge-derived stem cells in a mouse model of traumatic brain injury
Hair follicle stem cells might help treat traumatic brain injury.
research Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns
Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.
research 840 Early and late matrix progenitors form the terminally differentiated cell layers of the hair follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear
Ptprq has multiple forms that change during inner ear development.
research Zinc deficiency triggers hearing loss by reducing ribbon synapses of inner hair cells in CBA/N mice
Lack of zinc can cause hearing loss by damaging important parts of inner ear cells in mice.
research LSD1 is Required for Hair Cell Regeneration in Zebrafish
LSD1 is crucial for regenerating hair cells in zebrafish.