61 citations
,
December 2016 in “The EMBO Journal” The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.
Rat skin develops from a single layer to adult-like skin with hair follicles by day 21.
March 2022 in “Veterinary dermatology” A one-year-old cat had multiple benign skin tumors similar to those known in humans.
September 2019 in “Journal of Investigative Dermatology” Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.
5 citations
,
December 2016 in “Microscopy Research and Technique” EPI-NCSCs from hair follicles may help treat brain development issues in mice.
March 2024 in “Tissue and cell/Tissue & cell” Telomerase-positive cells are mainly in the bulb matrix and outer root sheath of hair follicles.
December 2021 in “Pathologica” Trichogerminoma is a rare, benign skin tumor from hair cells, with a small risk of becoming cancerous.
November 2024 in “Human Cell” Hair follicle stem cells can be turned into neuron-like cells, offering a new way for brain repair.
January 2012 in “Institutional Repositories DataBase (IRDB)” Cells from skin and lung can help regenerate hair follicles.
30 citations
,
January 1994 in “Micron” Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.
21 citations
,
July 2024 in “Journal of Investigative Dermatology” Fibroblasts change rapidly during wound healing, forming temporary niches before stabilizing into distinct scar layers.
10 citations
,
January 2020 in “Genes & Diseases” Circ-Smad5 slows cell growth by blocking a specific cell signaling pathway.
25 citations
,
October 2005 in “PubMed” Keratin 19 expression in certain skin cells is temporary and not a reliable stem cell marker.
43 citations
,
February 2008 in “Journal of cutaneous pathology” Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
82 citations
,
March 2016 in “Cell” The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
88 citations
,
January 1981 in “British Journal of Dermatology” A new method helps grow human hair cells using a cow eye lens.
16 citations
,
May 2017 in “Journal of Clinical Ultrasound” A rare finger tumor was imaged, showing a unique pattern not seen before.
4 citations
,
January 2011 in “Cell stem cell” Hair follicle stem cells can return to their original niche and help regenerate hair.
July 2025 in “Cell & Bioscience” Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
7 citations
,
October 2016 in “Cellular and Molecular Bioengineering” E-cadherin is important for cell movement in electric fields, and the new tracking method works well.
36 citations
,
March 2011 in “Nature Communications” Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.
38 citations
,
January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
11 citations
,
October 2001 in “Tissue engineering” Cultured epithelium can form hair follicles when combined with dermal papillae.
53 citations
,
January 2012 in “Developmental Biology” EGFR signaling is essential for ear cell regeneration in both birds and mammals.
19 citations
,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
45 citations
,
November 2022 in “Acta Biomaterialia” A new 3-D co-culture system improves hair growth potential in cells for hair regeneration.
75 citations
,
September 2017 in “Developmental biology” The circadian clock influences the behavior and regeneration of stem cells in the body.
8 citations
,
November 2015 in “The American journal of dermatopathology/American journal of dermatopathology” Punctate follicular porokeratosis is a skin condition with specific features seen in hair follicles.
May 2026 in “Signal Transduction and Targeted Therapy” BMP signaling is essential for forming skin structures called rete ridges, aiding skin thickness and regeneration.
January 2020 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” Polycomb Repressive Complex 1 is crucial for keeping stem cells stable and maintaining healthy adult tissues.