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GlossaryAplasia Cutis Congenita

congenital absence of skin, often on the scalp

Aplasia Cutis Congenita (ACC) is a rare congenital condition characterized by the absence of skin at birth, typically manifesting as a localized area without skin, most commonly on the scalp. The affected area can vary in size and may sometimes involve underlying structures such as bone or dura. While the exact cause is often unknown, ACC can be associated with genetic factors, teratogens, or other syndromes.

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Platelet-Rich Plasma Injection and Lipofilling-Assisted Hair Transplantation on Residual Scalp Alopecia Post Aplasia Cutis Congenita Verticis

research Platelet-rich Plasma Injection and Lipofilling-assisted Hair Transplantation on Residual Scalp Alopecia Post Aplasia Cutis Congenita Verticis (ACCV)

March 2025 in “International Journal of Trichology”

The combined treatment improved hair growth and scalp health in a patient with scalp alopecia from birth.

The Use of Human Dermal Papillae Conditioned Medium (HDPCM) on Aplasia Cutis Congenita in Lower Extremity Due to Intrauterine Varicella Infection

research The Use of Human Dermal Papillae Conditioned Medium (HDPCM) on Aplasia Cutis Congenita in Lower Extremity due to Intrauterine Varicella Infection

1 citations , March 2019 in “KnE life sciences”

HDPCM treatment healed a baby's congenital skin defect caused by varicella infection.

research Outcomes of Tissue Expander Application for Scalp Reconstruction in Extensive Aplasia Cutis Congenita

4 citations , November 2015 in “Aesthetic Plastic Surgery”

Using tissue expanders for scalp reconstruction in patients with extensive Aplasia Cutis Congenita is effective and has minimal complications.

research Aplasia cutis congenita on lumbosacral area

3 citations , January 2014 in “Indian dermatology online journal”

A newborn girl has a rare skin condition with two ulcers on her buttock that are healing on their own.

research Trichoscopy of aplasia cutis congenita of the scalp in skin of color

March 2023 in “Journal of Cosmetic Dermatology”

Trichoscopy is effective for diagnosing scalp ACC in darker skin tones.

research Two cases of aplasia cutis congenita with hair collar signs and macrophage hyperplasia

2 citations , June 2019 in “The Journal of Dermatology”

Two cases showed skin abnormalities without bone or neural defects.

research Methimazole, Carbimazole, and Congenital Skin Defects

132 citations , January 1987 in “Annals of Internal Medicine”

Methimazole may cause skin defects in babies if taken during pregnancy.

research Line-Field Optical Coherence Tomography: Usefulness in the Non-Invasive Differential Diagnosis of Congenital Alopecia of Infancy

July 2024 in “Dermatology Practical & Conceptual”

LC-OCT helps accurately diagnose different types of infant hair loss without invasive methods.

research Congenital and Hereditary Skin Diseases

January 2018

Goats can have various genetic skin diseases affecting hair, skin, and thyroid function.

research ‘Black dots’ seen under trichoscopy are not specific for alopecia areata

42 citations , June 2012 in “Clinical and Experimental Dermatology”

Black dots under trichoscopy can appear in different hair and scalp conditions, not just in alopecia areata.

research A case of temporal triangular alopecia

December 2020 in “TURKDERM”

A 3-year-old boy was diagnosed with a rare, non-scarring hair loss condition called temporal triangular alopecia.

Hair Loss in Children: A Detailed Overview of Pediatric Alopecia

research Hair Loss in Children

July 2018 in “Elsevier eBooks”

The most common cause of hair loss in children is tinea capitis, followed by alopecia areata and telogen effluvium.

research Localized Acquired Alopecia over the Mental Area of Chin

January 2022 in “Clinical Cases in Dermatology”

A 12-year-old boy has a rare, harmless hair loss on his chin with no need for treatment.

research Adams–Oliver syndrome: new evidence in variable expressivity?

December 2013 in “International Journal of Dermatology”

The clinical signs of Adams-Oliver syndrome can vary greatly, even among family members.

research Hair and nail disorders of childhood

7 citations , December 2008 in “Expert Review of Dermatology”

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

research Hair loss in infancy and childhood

1 citations , October 2014 in “Paediatrics and Child Health”

The document concludes that proper diagnosis and management of hair loss in children require a detailed examination and understanding of various hair disorders.

research Hair Disorders

November 2019 in “Harper's Textbook of Pediatric Dermatology”

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

research Hair loss in infancy and childhood

1 citations , January 2019 in “Paediatrics and Child Health”

The document concludes that understanding hair biology and recognizing hair conditions are crucial for managing and treating hair loss in children.

research Halo Scalp Ring: An Annular Alopecia Associated with Birth Injury

2 citations , January 2023 in “Annals of Dermatology”

A hairless patch on a boy's scalp from birth injury improved with minoxidil treatment.

research Committee on database of hair restoration results on patients with cicatricial alopecia and hair diseases other than androgenetic alopecia

September 2009 in “Hair transplant forum international”

A committee was formed to improve hair restoration for certain hair diseases by collecting and analyzing data.

research Hair loss in children.

6 citations , May 1993 in “Archives of Disease in Childhood”

Children's hair loss can be caused by many factors, including autoimmune diseases, emotional stress, genetics, and infections, with treatment and prognosis varying.

research What Work-Up Should Be Done for Patients With Alopecia?

May 2024 in “CRC Press eBooks”

Children's hair loss can have various causes, including infections, autoimmune issues, physical stress, nutritional problems, and genetic factors.

research Two Cases of Linear Alopecia on the Occipital Scalp

26 citations , January 2009 in “Annals of Dermatology”

Two rare bald spots on the back of the scalp were found to be lupus, not alopecia areata.

research Congenital Triangular Alopecia

January 2018 in “Springer eBooks”

Congenital triangular alopecia is a harmless, non-spreading hair loss condition often seen in young children.

research Inherited Hairlessness: A Case Study of Familial Congenital Atrichia

April 2023 in “Curēus”

The document concludes that the girl's hairlessness is likely inherited from her parents.

research Anterior, frontal congenital triangular alopecia, redundancy in therapy without improvement

5 citations , October 2018 in “Dermatologic therapy”

Recognizing congenital triangular alopecia is crucial to avoid unnecessary treatments.

research Congenital atrichia and hypotrichosis

11 citations , May 2011 in “World Journal of Pediatrics”

The document emphasizes the importance of correctly identifying and classifying genetic hair disorders to help diagnose related health conditions.

research Nevus Sebaceus With Novel HRAS Sequence Variant Mutation Misdiagnosed as Alopecia Areata

May 2023 in “Cutis”

A 12-year-old girl was misdiagnosed with alopecia areata but actually had a nevus sebaceus with a genetic mutation.

Atypical Congenital Triangular Alopecia (Brauer Nevus): Case Report and Literature Review in Occipital and Mid-Frontal Localizations

research Atypical Congenital Triangular Alopecia (Brauer Nevus): Case Report and Review of Literature in Occipital and Mid-Frontal Localizations

January 2021 in “Skin appendage disorders”

The report concludes that atypical Brauer nevus is more common in males, present at birth, and often misdiagnosed due to its unusual scalp locations.

research Congenital Combined Melanocytic Nevus of the Scalp With Associated Alopecia Areata

3 citations , August 2012 in “The American Journal of Dermatopathology”

A man with a birthmark on his scalp developed hair loss that improved with treatment, but the link between the birthmark and hair loss was unclear.