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LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

The ZIP13 variant is linked to abnormal hair quality.

Basonuclin helps identify and track hair follicle development and cycling in mice.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

ASH2L is essential for skin and hair development.

A specific RNA molecule, circCOL1A1, affects the growth and quality of goat hair by interacting with miR-149-5p and influencing cell growth pathways.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

Studying rare genetic disorders can help us understand and treat common diseases better.

Paxillin may help manage androgen-related disorders like PCOS by stabilizing androgen receptor proteins.

Spexin levels are lower in PCOS patients and linked to metabolic and hormonal issues.

PTCH gene mutations contribute to basal cell carcinoma development.

Desmosomes are crucial for skin and heart development, and JNK may help regulate them.

Non-coding RNAs may be key in diagnosing and treating rare skin disorders.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

Krox20 (Egr2) is important for the function of epithelial stem cells.

A new tool accurately identifies human cornea cell states and key factors.

Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.

KCNQ potassium channels help control the sensitivity of touch receptors in the skin.

Scientists created a cell model to study and find treatments for a skin disease called RDEB.

CTHRC1 is essential for healing and preventing heart rupture after a heart attack.

Basonuclin is crucial for hair follicle development and cycling in mice.

A new PAX9 gene mutation causes missing teeth and hair problems, but not skin or nail issues.

NFIB and STAT5 work together to control specific genetic programs in cells.

Hair root analysis can effectively detect somatic mosaicism in double cortex syndrome.