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Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.

5α-reductase inhibitors may reduce male fertility and could be used for male contraception.

Compound 15a was effective in inhibiting 5α-reductase.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

Different ligands change the shape of the TRPV3 ion channel in unique ways.

Combination drug therapies are more effective for high-risk BPS patients but have more side effects and costs.

20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.

Inhibiting testosterone 5alpha-reductase may help treat benign prostatic hyperplasia.

Stroma structural changes cause large pores and skin laxity, regardless of age or ethnicity.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

Nanospanlastic vesicles can improve glaucoma treatment by enhancing drug delivery to the eye.

Finasteride increases CD8+ T cells in BPH tissues.

Metyrapone effectively stabilizes severe Cushing's disease symptoms before surgery.

Spironolactone and clascoterone are promising acne treatments with fewer side effects.

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

Radiofrequency devices effectively tighten skin without surgery.

Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Testosterone reduces knee flexibility by affecting relaxin receptors.

Combination therapy with fesoterodine and doxazosin improves bladder function and delays BPH progression.

Antiandrogens may help prevent or treat COVID-19 by blocking virus entry into cells.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

Botulinum toxin injections effectively relieve pain from cutaneous leiomyomas.

New compounds show promise for treating benign prostate hyperplasia with fewer side effects.

PDE5 inhibitors cause earlier adverse events in BPH treatment, requiring careful monitoring.

Alpha-blockers are the most effective and widely used treatment for lower urinary tract symptoms, with minimal side effects.