January 2024 in “Theranostics” HDAC6 helps keep ovarian follicles dormant, extending female fertility.
April 2017 in “Journal of Pharmaceutical Investigation” Indole-based compounds improved ovarian health in rats with PCOS, with L-Tryptophan and Tryptophol being most effective.
December 2006 in “Annales D Endocrinologie” Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.
16 citations
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May 2020 in “Frontiers in pharmacology” Minoxidil can stop the growth of ovarian cancer cells without harming the heart.
June 2023 in “Journal of multidisciplinary sciences (Online)” PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.
13 citations
,
September 2018 in “Scientific Reports” The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.
Reducing iron levels didn't improve heart health or metabolism in women with certain ovarian issues.
Resveratrol improved hormone levels, menstrual cycles, hair loss, and ovarian function in PCOS patients.
October 2018 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and more heart and blood vessel risk factors, especially if their condition is not well-controlled.
December 2023 in “Frontiers in endocrinology” Excess androgens may cause PCOS, not just be a symptom.
June 2023 in “Journal of multidisciplinary sciences” PCOS may increase the risk of certain cancers.
41 citations
,
January 2020 in “Journal of Ovarian Research” Quercetin may help with PCOS symptoms, but more research is needed.
40 citations
,
December 2016 in “Journal of Ovarian Research” Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.
75 citations
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November 2007 in “Clinical endocrinology” Certain medications including flutamide, spironolactone, and others effectively reduce excessive hair growth in women, especially when combined with lifestyle changes.
9 citations
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July 2022 in “International Journal of Molecular Sciences” Prenatal THC exposure may harm ovarian health and fertility.
January 2022 in “Kafkas Universitesi Veteriner Fakultesi Dergisi” The research improved understanding of twin births and fertility in Tibetan sheep, helping animal farming.
37 citations
,
February 2010 in “Psychoneuroendocrinology” Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
23 citations
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July 1989 in “Postgraduate medical journal” Spironolactone did not make hair thinner in women with excess hair growth.
17 citations
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June 1997 in “Baillière's clinical obstetrics and gynaecology” Scientists now better understand how human hair growth is controlled, including the roles of specific genes and proteins.
3 citations
,
March 2023 in “International journal of molecular sciences” Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
13 citations
,
October 2022 in “Reproductive Biology and Endocrinology” A new hyaluronan-based biomatrix successfully supports the growth of mouse ovarian follicles, producing healthy eggs.
21 citations
,
September 2017 in “Journal of Obstetrics and Gynaecology Research” Chromium supplements don't improve insulin, hormone levels, or cholesterol in women with PCOS but raise testosterone levels.
16 citations
,
July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada” Birth control pills can help reduce mild to moderate acne in women.
7 citations
,
August 2022 in “Journal of Nanobiotechnology” Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.
3 citations
,
August 2004 in “International journal of gynaecology and obstetrics” Finasteride doesn't change polycystic ovary size or cyst number, suggesting testosterone's role in their appearance.
110 citations
,
August 2015 in “Neuropsychopharmacology” High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.
28 citations
,
May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.
6 citations
,
February 2016 in “British Journal of Dermatology” A woman with a drug allergy to anakinra was successfully desensitized, allowing her to continue treatment without allergic reactions.
1 citations
,
March 2021 in “Journal of Experimental Biology and Agricultural Sciences” Flaxseed crackers can help reduce symptoms of PCOS in young women.
1 citations
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October 2010 in “Cambridge University Press eBooks” Hormonal therapies are effective for managing hair and skin symptoms in women with PCOS.