Scalp cooling is recommended to prevent chemotherapy-induced hair loss, but no effective drugs are available.
4 citations
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March 2024 in “Journal of the American Academy of Dermatology” Scalp cooling therapy is costly and often not covered by insurance, limiting access for low-income patients.
4 citations
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November 2000 in “Dermatologic surgery” The cooling gel reduces pain during laser hair removal.
January 2021 in “Mastology” Scalp cooling therapy helped over 80% of women keep at least half their hair during chemotherapy.
December 2025 in “npj Systems Biology and Applications” Cold temperatures can stop human cell circadian rhythms, but warming restores them.
February 2023 in “Sibirskij onkologičeskij žurnal” Chemotherapy often causes hair loss in cancer patients, affecting their mental health, but scalp cooling can help prevent it.
2 citations
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June 1987 in “British Journal of Dermatology” Warming hands improves blood flow in people with systemic sclerosis.
February 2026 in “Clinical Cancer Research” The combined treatment helped prevent hair loss and promoted full hair regrowth in breast cancer patients after chemotherapy.
34 citations
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January 2018 in “International Journal of Dermatology” Scalp cooling is the most effective FDA-approved method to prevent chemotherapy-induced hair loss, but more research is needed for other treatments.
Some cancer treatments cause different types of hair loss, but scalp cooling can help prevent it.
17 citations
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October 2012 in “European Journal of Pharmacology” Toluene lowers body temperature through different mechanisms depending on the concentration.
April 2023 in “Journal of Investigative Dermatology” Keeping human skin stem cells is easier with low temperatures and mTOR inhibition.
May 1999 in “Dermatologic Surgery” Using an ultrasonic liposuction machine with different cannula sizes and power settings does not change water temperature.
1 citations
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February 2002 in “Dermatologic Surgery” A cheap stainless steel container from a retail store can store liquid nitrogen effectively for 8-12 hours, saving money for medical practitioners.
March 2025 in “Pain Physician” Cooling the skin before injections reduces pain for patients with hair loss.
March 2025 in “International Journal of Trichology” Storing hair follicles in 10% DMEM at 37°C improves hair transplant success.
February 2002 in “Dermatologic Surgery” A cheap stainless steel container from a retail store can store liquid nitrogen effectively for 8-12 hours, offering a cost-effective alternative to specialized medical containers.
September 2016 in “Aktualʹnì pitannâ farmacevtičnoï ì medičnoï nauki ta praktiki” The minoxidil cream-mask is stable and effective for hair growth when prepared at 60-80ºC.
3 citations
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November 2018 in “Oncology issues” Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair follicles can be kept in RNAlater® at cool or room temperature for a week without harming RNA quality.
8 citations
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February 2018 in “European journal of oncology nursing” The Hair Check tool can measure hair loss, but patients' own reports are more reliable for assessing hair loss during chemotherapy.
August 2025 in “Arabixiv (OSF Preprints)” Male pattern baldness is mainly caused by brain heat stress, not DHT.
September 2024 in “Journal of the American Academy of Dermatology” Facebook groups play a crucial role in supporting and guiding patients on scalp cooling and hair loss during chemotherapy.
2 citations
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January 2017 in “Indian Dermatology Online Journal” A rare skin reaction from laser hair removal can be prevented with medication.
1 citations
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January 2025 in “JAAD reviews.” Personalized hair care strategies are needed for Black cancer patients to prevent hair loss during chemotherapy.
11 citations
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January 2022 in “Methods in cell biology” 21 citations
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June 2023 in “Proceedings of the National Academy of Sciences” Tightly curled scalp hair helps reduce heat from the sun, protecting against overheating.
4 citations
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June 2019 in “International Journal of Cosmetic Science” Heat transfer in hair is slower in groups of hair, increasing the risk of damage from high-temperature styling tools.
5 citations
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November 2002 in “Aesthetic Plastic Surgery” Storing hair follicles at -20°C keeps them good for up to 15 days, which may help with hair transplants.
March 2026 in “Medical Lasers” Adjusting hair dryer settings improves drying efficiency and keeps hair healthy.