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research Three-dimensional modelling of interchain sequence similarities and differences in the coiled-coil segments of keratin intermediate filament heterodimers highlight features important in assembly

13 citations , November 2007 in “Journal of Structural Biology”

Keratin heterodimers are preferred for their specific and structural advantages.

research Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure

51 citations , January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology”

Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.

research H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development

1 citations , August 2025 in “Epigenetics & Chromatin”

H3K4me3 helps control RSPO3 to influence hair growth and development.

research Complete sequence of a hair-like intermediate filament type II keratin gene

15 citations , January 1993 in “DNA sequence”

KRT2.13 gene is similar to KRT2.9 but not expressed in hair follicles.

research Amino Acid Compositions of Human Hair Fibrous Protein Components Purified with Two‐dimensional Electrophoresis

4 citations , December 1989 in “The Journal of Dermatology”

Human hair proteins have similar cysteine and glycine levels to skin proteins.

research Molecular and functional aspects of the hairless (hr) gene in laboratory rodents and humans

126 citations , October 1998 in “Experimental Dermatology”

The hr gene is crucial for skin and hair health, with mutations causing hair disorders.

research Ontogeny and regional variability of keratin 2e (K2e) in developing human fetal skin: a unique spatial and temporal pattern of keratin expression in development

19 citations , April 1999 in “British Journal of Dermatology”

Keratin 2e shows a unique pattern in developing fetal skin, different from other keratins.

research An ultrahigh-sulphur keratin gene of the human hair cuticle is located at 11q13 and cross-hybridizes with sequences at 11p15

15 citations , January 1991 in “Mammalian Genome”

research Hair Keratins and Hair Follicle–Specific Epithelial Keratins

31 citations , January 2004 in “Methods in cell biology”

Hair and follicle keratins differ in structure and expression, especially in cysteine content.

research Immunological characteristics and histological distribution of human hair fibrous proteins studied with anti-hair keratin monoclonal antibodies HKN-2, HKN-4, and HKN-6.

52 citations , February 1986 in “Journal of Histochemistry & Cytochemistry”

Some hair proteins are specific to hair, while others are also found in skin cells.

research Microtubule associated protein (MAP‐2) expression defines the companion layer of the anagen hair follicle and an analogous zone in the nail unit

14 citations , October 2002 in “Journal of cutaneous pathology”

MAP-2 is crucial for the structure of hair follicles and nails.

research Two Different Mutations in the Same Codon of a Type II Hair Keratin (hHb6) in Patients with Monilethrix

20 citations , December 1999 in “Journal of Investigative Dermatology”

Mutations in the hHb6 gene cause the hair disorder monilethrix.

research Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13

47 citations , September 2004 in “Journal of Biological Chemistry”

Hoxc13 regulates specific hair protein genes on mouse chromosome 16.

research Comparative immunohistochemical analysis suggests a conserved role of EPS8L1 in epidermal and hair follicle barriers of mammals

1 citations , October 2023 in “PROTOPLASMA”

research Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11*1

1 citations , May 2004 in “Biochemical and Biophysical Research Communications”

Two new gene clusters important for hair formation were found on human chromosome 11.

research Characterization of a Hair (Wool) Keratin Intermediate Filament Gene Domain

40 citations , February 1994 in “Journal of Investigative Dermatology”

research 591 Chromatin architectural protein CTCF regulates terminal keratinocyte differentiation in the developing epidermis and hair follicles

April 2021 in “The journal of investigative dermatology/Journal of investigative dermatology”

CTCF protein is essential for skin and hair follicle development in mice.

research Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues.

57 citations , January 1987 in “Journal of Biological Chemistry”

Different keratins have unique expression patterns in mouse skin cells.

research Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11

27 citations , April 2004 in “Biochemical and Biophysical Research Communications”

Two new gene clusters important for hair formation were found on human chromosome 11.

research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle

1 citations , February 1991 in “Journal of Biological Chemistry”

research The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation

166 citations , July 1999 in “American Journal Of Pathology”

The hairless (hr) gene is essential for normal hair follicle function and its mutation leads to hair loss.

research Characterization of New Members of the Human Type II Keratin Gene Family and a General Evaluation of the Keratin Gene Domain on Chromosome 12q13.13

92 citations , February 2005 in “Journal of Investigative Dermatology”

research Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation

16 citations , April 2024 in “Proceedings of the National Academy of Sciences”

HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.

research Proteome Analysis of Human Hair Shaft

122 citations , January 2006 in “Molecular & Cellular Proteomics”

Human hair contains many proteins, with some being highly abundant and modified.

research KRT72 wt Allele

February 2020 in “Definitions”

KRT72 gene helps form hair.

The Human Type I Keratin Gene Family: Characterization of New Hair Follicle Specific Members and Evaluation of the Chromosome 17q21.2 Gene Domain

research The human type I keratin gene family: Characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain

70 citations , December 2004 in “Differentiation”

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

research Chromosomal localization of acidic and basic keratin genes of the domestic dog

9 citations , April 1999 in “Mammalian Genome”

Acidic keratin genes are on CFA9 and basic keratin genes are on CFA27 in dogs.

research Ultrastructural Localization of Hair Keratins in Human Scalp Hair Shafts as Revealed by Rapid-Freezing Immunocytochemistry.

3 citations , January 1998 in “ACTA HISTOCHEMICA ET CYTOCHEMICA”

Hair keratins are mainly on macrofibrils in the cortex and in the endocuticle in the cuticle.

research Keratin expression in the human hair follicle

1 citations , January 1989 in “Springer eBooks”

research The Fate of Trichohyalin

135 citations , October 1997 in “Journal of biological chemistry/The Journal of biological chemistry”

Trichohyalin is modified by enzymes to form strong structures in hair cells.

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