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research A nanocomposite competent to overcome solubility and permeation issues of capsaicin and thiocolchicoside simultaneously in gout management: Fabrication of nanocubosomes

6 citations , March 2024 in “Saudi Pharmaceutical Journal”

The new delivery system could improve pain and inflammation relief in gout.

[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs

research [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) inhibits SCF/c-kit signaling in 501mel human melanoma cells and abolishes melanin production in mice and brownish guinea pigs

26 citations , July 2007 in “Biochemical Pharmacology”

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

research Neurosteroid influence on affective tone

19 citations , July 2023 in “Neuroscience & Biobehavioral Reviews”

Endogenous neurosteroids may set a baseline mood.

research Comparison of Finasteride (Proscar®) and Serenoa repens (Permixon®) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers

73 citations , January 1994 in “European Urology”

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

research Tranexamic acid reduces inflammation, edema and burn wound conversion in a rodent model

8 citations , February 2024 in “Burns”

research The Flavonol Quercitrin Hinders GSK3 Activity and Potentiates the Wnt/β-Catenin Signaling Pathway

21 citations , October 2022 in “International Journal of Molecular Sciences”

Quercitrin may help treat Alzheimer's by boosting brain cell signaling without causing tumors.

research Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors

13 citations , January 2005 in “Chemical and Pharmaceutical Bulletin”

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

research 5α-Reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives

26 citations , October 2011 in “International Journal of Biological Macromolecules”

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

research Minoxidil cyclodextrin inclusion complex-loaded microemulsions and transfersomes for androgen alopecia treatment: a comparative study

1 citations , April 2025 in “Drug Delivery and Translational Research”

research Finasteride/minoxidil

January 2025 in “Reactions Weekly”

research Finasteride/minoxidil

November 2024 in “Reactions Weekly”

research Finasteride/minoxidil

May 2023 in “Reactions Weekly”

research Drug Repurposing Patent Applications July–September 2025

January 2025 in “Drug repurposing”

New drug uses show promise but need more research.

research Mineralocorticoid Receptor Antagonists—A New Sprinkle of Salt and Youth

8 citations , October 2016 in “Journal of Investigative Dermatology”

MR antagonists may improve skin health and wound healing, especially in aging.

research Carbobenzoxy-capped Phe-Lys(BODIPY TMR-X-acyloxymethyl ketone(QSY7)

May 2010 in “Europe PMC (PubMed Central)”

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

research The Administration of Ocoxin Increases the Quality of Life of Patients with Advanced Epithelial or Metastatic Ovarian Cancer Undergoing Neoadjuvant Chemotherapy

1 citations , January 2022 in “Journal of Cancer Therapy”

Ocoxin improves quality of life for advanced ovarian cancer patients on chemotherapy.

research Targeting cardiac hypertrophy through a nuclear co‐repressor

3 citations , October 2019 in “EMBO molecular medicine”

Targeting NCoR1 can help treat heart enlargement and dysfunction.

research Synthetic Approaches for Pharmacologically Active Decorated Six-Membered Diazines

January 2023 in “IntechOpen eBooks”

The document concludes that specific methods for making diazine-based drugs can lead to high yields and are important for creating effective treatments for various diseases.

research Patent Evaluation: Δ-4,6-Steroids as Potent 5α-Reductase Inhibitors

April 1992 in “Current opinion in therapeutic patents”

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis

March 2026 in “Preprints.org”

DRDE-07 shows promise for treating skin diseases due to its favorable properties.

research PC-SPES Studies Promising, But Manufacturer Shuts Down

September 2002 in “Oncology Times”

Promising cancer treatments were found, but the manufacturer closed.

Ionizable Coenzyme-Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases

research Ionizable Coenzyme‐Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases

October 2025 in “Advanced Materials”

New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.

research Health Canada has approved finasteride [Proscar; Merck Frosst] and doxazosin cotherapy

September 2004 in “Inpharma Weekly”

research Effects of Periplaneta americana extracts on the growth and proliferation of cutaneous interstitial cells in cutaneous-wound healing

9 citations , August 2022 in “Frontiers in Pharmacology”

Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.

Comparison of Ruxolitinib and a Collagen-Targeted PTH-Based Hair Cycle Stimulant on Hair Follicle Counts and Hair Growth in the C3H/HeJ Engrafted Mouse Model of Alopecia Areata

research ISID1108 - Comparison of ruxolitinib and a collagen-targeted PTH-based hair cycle stimulant on hair follicle counts and hair growth in the C3H/HeJ engrafted mouse model of alopecia areata.

May 2023

The PTH-CBD injection improved hair regrowth better than the daily ruxolitinib pill in mice.

research Tuning Scaffold Properties of New 1,4-Substituted Pyrrolo[3,2-c]quinoline Derivatives Endowed with Anticancer Potential, New Biological and In Silico Insights

December 2025 in “Biomolecules”

Compound 7p shows strong potential as an anticancer agent.

research Biocompatible exosomes derived from Pinctada martensii mucus for therapeutic melanin regulation via α-MSH/NF-κB/MITF pathway

1 citations , January 2025 in “Regenerative Biomaterials”

Exosomes from Pinctada martensii mucus can safely reduce melanin production, offering a new treatment for skin pigment issues.

research Roxithromycin-loaded lipid nanoparticles for follicular targeting

35 citations , October 2015 in “International Journal of Pharmaceutics”

Tiny particles carrying roxithromycin can effectively target and deliver the drug to hair follicles without irritation.

research Intracellular Calcium Mobilization in Response to Ion Channel Regulators via a Calcium-Induced Calcium Release Mechanism

19 citations , December 2016 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

research Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1

3 citations , June 2018 in “Bioorganic & medicinal chemistry”

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

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