162 citations
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December 2008 in “Stem Cells” Hair follicle stem cells can become corneal-like cells, potentially helping restore vision.
135 citations
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October 2010 in “Stem Cells” Hair follicle stem cells can help treat eye surface issues by becoming corneal cells.
130 citations
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February 2005 in “Proceedings of the National Academy of Sciences” Corneal cells can transform into skin and hair cells through specific signals.
55 citations
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January 2004 in “The International Journal of Developmental Biology” Corneal cells can transform into hair-producing skin cells when exposed to certain signals.
20 citations
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April 2009 in “Cell Biology International” Hair follicle stem cells can become corneal-like cells with the help of pax6.
15 citations
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August 2020 in “American Journal of Pathology” Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.
14 citations
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April 2017 in “Scientific Reports” Using a perfusion system and 3D spheroid culture improves the growth of corneal cell layers for tissue engineering.
3 citations
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January 2018 in “BIO-PROTOCOL” Hair follicle stem cells can be transplanted onto the eye using a fibrin carrier to help repair eye damage.
2 citations
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June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Corneal regeneration relies on distinct stem cell compartments in the limbal niche.
January 2025 in “Frontiers in Cell and Developmental Biology” Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
January 2025 in “Open Life Sciences” Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.
June 2022 in “Indian Journal of Ophthalmology/Indian journal of ophthalmology” Early and aggressive treatment is crucial for preserving vision in infants with AEC syndrome.
January 2020 in “Työväentutkimus Vuosikirja” Corneal health relies on cell migration and cooperation with the lacrimal gland, not Bmi1+ cells, and Eda gene mutations can cause dry eye disease.
April 2018 in “Journal of Investigative Dermatology” The conclusion is that the cornea has two types of stem cells, with Lrig1+ cells being key for renewal in aging corneas, independent of CD44.
December 2012 in “Canadian journal of ophthalmology” Eyelash transplantation can cause eye damage and pain if not done carefully.
Thymosin β4 helps heal corneal wounds.
August 2009 in “Mechanisms of Development” Adult hair follicle cells can create new hair follicles from corneal cells with the right support.
September 2008 in “Acta Ophthalmologica” Hair follicle stem cells can become corneal-like cells with the right environment.
January 2006 in “Elsevier eBooks” Most vertebrates can regenerate skin, nails, and corneas, but only some can regenerate teeth and lenses.
July 2025 in “PNAS Nexus” A new tool accurately identifies human cornea cell states and key factors.
Wnt7a helps corneal cells grow and stick together, aiding in repair.
28 citations
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January 1997 in “Elsevier eBooks” Keratinocyte stem cells help regenerate and repair cornea, skin, and hair.
January 2008 in “Di-san junyi daxue xuebao” Rat hair follicle stem cells can become corneal epithelium-like cells when exposed to rabbit corneal limbal stroma.
5 citations
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January 2019 in “Methods in molecular biology” Multiphoton microscopy can effectively image live cells in cornea, skin, and hair follicles over time.
11 citations
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January 2024 in “Regenerative Biomaterials” A new 3D-printed hydrogel scaffold helps regenerate corneas and prevent scarring.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” People in the Aseer region of Saudi Arabia need more information and understanding about corneal donation.
46 citations
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September 2010 in “Veterinary Dermatology” Many alpacas have skin diseases, with bacterial infections being the most common.
295 citations
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June 2009 in “Science” Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
94 citations
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January 2007 in “Cutaneous and Ocular Toxicology” Iranian veterans exposed to sulfur mustard suffer from long-term skin itching and eye damage, with some risk of skin cancer and ongoing management challenges.
54 citations
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September 2012 in “Acta ophthalmologica” Cancer treatments can cause various eye problems, so eye doctors should know how to diagnose and treat these early.