November 2025 in “Journal of Investigative Dermatology” Mesenchymal stiffness affects sweat gland cell development.
46 citations
,
November 2007 in “Gene Expression Patterns” Trps1 plays a key role in hair follicle development and cycling.
30 citations
,
January 2013 in “Human Mutation” A mutation in the HOXC13 gene causes hair and nail problems in a Syrian family.
11 citations
,
June 1994 in “Journal of Investigative Dermatology”
54 citations
,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
April 2018 in “Journal of Investigative Dermatology” Ceramide synthase 4 is essential for maintaining skin barrier health.
July 2024 in “Journal of Investigative Dermatology” Mechanical tension worsens keloid scars by activating inflammation and fibrosis pathways.
May 2022 in “Experimental dermatology” Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
156 citations
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January 1989 in “Genes & Development” Keratin expression reflects cell organization and differentiation, not causes it.
11 citations
,
January 1997 in “Journal of Dermatological Science” A new protein linked to hair strength was identified, aiding in understanding brittle hair conditions.
7 citations
,
May 2024 in “Tissue Barriers” The skin's outer layer relies on lipids and proteins to protect against damage.
May 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” β-Catenin is essential for new hair growth after skin injury.
21 citations
,
December 2015 in “European journal of cell biology” Tight junctions create a barrier in pig hair follicles that controls what can enter the skin.
May 2020 in “International journal of dermatology and venereology” Hair matrix cysts are rare skin nodules with unique features, often needing surgical removal.
September 2016 in “Journal of dermatological science” Collagen XVII is crucial for skin cell growth and nail health.
4 citations
,
January 2004 in “Biological and Pharmaceutical Bulletin” AgK114 protein helps in hamster skin injury recovery.
May 2026 in “Journal of Proteomics” 110 citations
,
August 2004 in “British Journal of Dermatology” The ventral matrix is the main source of the nail plate.
5 citations
,
January 2016 in “Stem Cells International” Certain skin cells near the base of hair muscles may help renew and stabilize skin, possibly affecting skin disorder understanding.
135 citations
,
October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin is modified by enzymes to form strong structures in hair cells.
3 citations
,
December 2008 in “Frontiers of Agriculture in China” The Cashmere goat hair keratin gene is crucial for hair structure.
6 citations
,
January 2022 in “Gene” Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.
95 citations
,
March 2009 in “Differentiation” Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
November 2024 in “Research Square (Research Square)” Moracin M boosts hair growth by activating key pathways and promoting cell growth.
January 2026 in “Aging and Disease” The Dickkopf (DKK) protein family, known for regulating the Wnt signaling pathway, has been increasingly recognized for its roles in non-cancerous diseases such as osteoporosis, arthritis, chronic kidney disease, myocardial injury, neurodegenerative conditions like Alzheimer's disease, and dermatological issues including alopecia. Recent research highlights the potential of DKK proteins as diagnostic biomarkers and therapeutic targets in these disorders. This review synthesizes findings from the past three years, exploring the DKK family's pathophysiological roles and clinical relevance, and discusses the challenges and opportunities in leveraging these proteins for diagnosis and treatment.
57 citations
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May 2016 in “Matrix Biology” Laminin α5 is essential for skin communication and health.
8 citations
,
January 2013 in “genesis” Zfp157 is active in many mouse tissues during development and in specific adult cells.
2 citations
,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
15 citations
,
February 2020 in “Journal of Investigative Dermatology” Ceramide Synthase 4 is crucial for healthy skin barrier function.
15 citations
,
October 1999 in “British Journal of Dermatology” Collagen remodeling is more active during hair growth stages.