research Wnt-10b secreted from lymphocytes promotes differentiation of skin epithelial cells
Wnt-10b helps skin cells and hair grow.
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research Trichothiodystrophy hair shafts display distinct ultrastructural features
Trichothiodystrophy hair is structurally abnormal with protein and organization issues.
research KY19382 Accelerates Cutaneous Wound Healing via Activation of the Wnt/β-Catenin Signaling Pathway
KY19382 speeds up wound healing by activating a specific cell signaling pathway.
research Hair-Cycle-Dependent Expression of Parathyroid Hormone-Related Protein and its Type I Receptor: Evidence for Regulation at the Anagen to Catagen Transition
Parathyroid hormone-related protein helps control hair growth phases in mice.
research 186 Dissecting the role of the common neurotrophin receptor CD271 in the skin: generation and characterization of a novel mouse model with keratinocyte-specific conditional deletion
Deleting the CD271 gene in mouse skin cells leads to disorganized skin and increased hair growth, suggesting CD271 is important for skin health.
research Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healing
Activating ER-β, not ER-α, improves skin cell growth and wound healing.
research Morpho‐regulation in diverse chicken feather formation: Integrating branching modules and sex hormone‐dependent morpho‐regulatory modules
Sex hormones, especially estradiol, can change chicken feather shapes and colors.
research 474 Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility
Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
research 090 Stromal re-organization in hair follicle development and cancer suppression
Activating Sonic Hedgehog signaling in cancer stroma may help treat basal cell carcinoma.
research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis
Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.
research Corrigendum to “Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro” [Eur. J. Cell Biol. (2010) 769–777]
The authors clarified data overlap and corrected a figure error, apologizing for any confusion.
research Additional file 6 of Time-course RNA-seq analysis reveals stage-specific and melatonin-triggered gene expression patterns during the hair follicle growth cycle in Capra hircus
Melatonin affects different genes and pathways important for goat hair growth.
research AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma
AP-1 and TGFß work together to drive resistance in basal cell carcinoma, suggesting new treatment options.
research 700 Oncostatin M is upstream of JAK-STAT signaling during the murine hair cycle
Blocking Oncostatin M's role in the JAK-STAT pathway can stimulate hair growth in mice.
research Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling
Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.
research Connective tissue sheath of hair follicle is a major source of dermal type I procollagen in human scalp
The hair follicle's connective tissue is a key source of a certain collagen in human scalp skin.
research Immunofluorescent localization of collagen types I, III and IV, fibronectin, laminin, and basement membrane proteoglycan in developing mouse skin
research The CAP1/Prss8 catalytic triad is not involved in PAR2 activation and protease nexin‐1 (PN‐1) inhibition
CAP1/Prss8 does not activate PAR2 or inhibit PN-1.
research Local structure of human hair spatially resolved by sub-micron X-ray beam
Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.
research Expression of nicastrin, NICD1, and Hes1 in NCSTN knockout mice: implications for hidradenitis suppurativa, Alzheimer’s, and liver cancer
research Transcriptome analysis reveals the genetic basis underlying the development of skin appendages and immunity in hedgehog (Atelerix albiventris)
The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.
research STUDY ON CONNECTIVE TISSUE FIBRE IN NECK SKIN OF GOAT
Goat neck skin has a complex network of collagen, elastic, and reticular fibers.
research In Vitro Assembly and Structure of Trichocyte Keratin Intermediate Filaments
Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.
research An implication for post-transcriptional control: Reciprocal changes of melanocortin receptor type 2 mRNA and protein expression in alopecia areata
Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
research 1301 STIM1, but not STIM2, is the calcium sensor critical for sweat secretion
STIM1 is essential for sweat secretion.
research Wnt/β-catenin signaling pathway activates melanocyte stem cells in vitro and in vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Gene network analysis reveals candidate genes related with the hair follicle development in sheep
Key genes crucial for sheep hair follicle development were identified, aiding fine wool breeding and human hair loss research.
research Bone morphogenetic protein signaling regulates the size of hair follicles and modulates the expression of cell cycle-associated genes
BMP signaling controls hair follicle size and cell growth by affecting cell cycle genes.
research Modulation of Vitamin D Receptor Activity by the Corepressor Hairless: Differential Effects of Hairless Isoforms
Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.