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research Disturbed Keratinocyte Differentiation in Transgenic Mice and Organotypic Keratinocyte Cultures as a Result of Spermidine/Spermine N1-Acetyltransferase Overexpression

37 citations , February 2005 in “Journal of Investigative Dermatology”

Overexpression of SSAT causes hair loss and skin issues, but reducing putrescine can help.

research Common Skin Disorders in Pediatric Skin of Color

35 citations , October 2019 in “Journal of pediatric health care”

Children with darker skin tones can have specific skin conditions that need tailored treatments.

research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin

35 citations , January 2011 in “Journal of Biological Chemistry”

sPLA2-X is crucial for normal hair growth and follicle health.

research The regulation of skin homeostasis, repair and the pathogenesis of skin diseases by spatiotemporal activation of epidermal mTOR signaling

35 citations , July 2022 in “Frontiers in Cell and Developmental Biology”

Proper mTOR signaling is crucial for healthy skin and preventing skin diseases.

research Protein Kinase C δ Overexpressing Transgenic Mice Are Resistant to Chemically but not to UV Radiation–Induced Development of Squamous Cell Carcinomas: A Possible Link to Specific Cytokines and Cyclooxygenase-2

35 citations , January 2006 in “Cancer Research”

Mice with extra PKCδ resist chemical-induced skin cancer but not UV-induced.

research Miz1 is required for hair follicle structure and hair morphogenesis

33 citations , July 2007 in “Journal of cell science”

Miz1 is essential for proper hair structure and growth.

research Targeting the Complexity of In Vitro Skin Models: A Review of Cutting-Edge Developments

32 citations , August 2024 in “Journal of Investigative Dermatology”

In vitro skin models are improving but still need more innovation to fully replicate human skin.

research Progress in Topical and Transdermal Drug Delivery Research—Focus on Nanoformulations

32 citations , June 2024 in “Pharmaceutics”

Nanoformulations improve drug delivery through the skin, reducing side effects and enhancing effectiveness.

A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells

research A systematic summary of survival and death signalling during the life of hair follicle stem cells

31 citations , August 2021 in “Stem Cell Research & Therapy”

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

research Keratinocyte-Specific Onset of Serine Protease BSSP Expression in Experimental Carcinogenesis

26 citations , September 2001 in “Journal of Investigative Dermatology”

BSSP may help skin tumors grow and could be a marker or target for skin cancer treatment.

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