research Activation of the integrated stress response in human hair follicles
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
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600-630 / 1000+ results research Greater conversion of testosterone to 5α-dihydrotestosterone, reflecting increased peripheral 5α-reductase activity in nude mice treated with high doses of cyclosporine A
High doses of cyclosporine A increase testosterone conversion, possibly boosting hair growth.
research An Uncontrolled Case Series Using a Botanically Derived, β-Cyclodextrin Inclusion Complex in Two Androgenetic Alopecia-Affected Male Subjects
Herbal formula shows promise for hair loss treatment.
research Topical Metformin Compared with Clobetasol Propionate for Alopecia Areata: Clinical Outcomes from a Comparative Study
Clobetasol is more effective than metformin for treating localized alopecia areata.
research Hydroxylation of dehydroepiandrosterone in human scalp hair folhcles
The enzyme system in hair follicles is similar to the liver's and is affected by certain inhibitors.
research Steroid Biomarkers and Genetic Studies Reveal Inactivating Mutations in Hexose-6-Phosphate Dehydrogenase in Patients with Cortisone Reductase Deficiency
Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
research The local hypothalamic–pituitary–adrenal axis in cultured human dermal papilla cells
Stress hormone CRF causes hair loss and inhibits hair growth in human cells.
research Neurosteroidogenesis Is Required for the Physiological Response to Stress: Role of Neurosteroid-Sensitive GABAAReceptors
Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
research Poria cocos polysaccharides attenuate chronic nonbacterial prostatitis by targeting the gut microbiota: Comparative study of Poria cocos polysaccharides and finasteride in treating chronic prostatitis
Poria cocos polysaccharides and finasteride both help treat chronic nonbacterial prostatitis, but Poria cocos polysaccharides also improve gut health.
research Facile fabrication of cedrol nanoemulsions with deep transdermal delivery ability and high safety for effective androgenic alopecia treatment
Cedrol nanoemulsions effectively treat hair loss by promoting hair growth and reducing DHT levels safely.
research A computational approach to mechanistic and predictive toxicology of pesticides
Pesticides can cause reproductive and adrenal health issues.
research Endogenous steroid hormones in hair: Investigations on different hair types, pigmentation effects and correlation to nails
Body hair isn't a good substitute for scalp hair in steroid analysis.
research Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size
Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.
research Efficacy and Safety of Topical Corticosteroid Treatment under Occlusion for Severe Alopecia Areata in Children. A single-center retrospective analysis
Topical corticosteroids may be a safe and effective treatment for severe alopecia areata in children.
research PCA: A tFNA-based targeted nucleic acid nanocomposite hydrogel for the treatment of androgenetic alopecia through the promotion of angiogenesis and hair follicle stem cell proliferation
PCA hydrogel promotes hair growth by enhancing blood vessel formation and hair follicle stem cell activity.
research Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis
Type XVII collagen helps control skin cell growth and rejuvenates skin.
research Central serous chorioretinopathy after scalp and eyebrow intralesional triamcinolone acetonide injections: Report of two cases
Corticosteroid injections for hair loss may cause eye problems, so caution is needed.
research In silico screening of effective inhibitor of 5α-reductase type 1 for androgenic alopecia treatment
β-sitosterol and brassicasterol may help treat hair loss.
research Promoting effect of type 17 collagen production by chlorogenic acid using PLGA nanoparticles in the human epidermal keratinocyte cell
Encapsulating chlorogenic acid in nanoparticles boosts type 17 collagen production, potentially aiding skin care.
research DIFFERENTIAL STRIPPING TECHNIQUE TO DETERMINE FINASTERIDE RETENTION IN HAIR FOLLICLES AFTER IN VITRO TOPICAL APPLICATION
research Cyproterone acetate-loaded nanostructured lipid carriers: effect of particle size on skin penetration and follicular targeting
Smaller particles of the drug carrier penetrated skin better, with 300 nm size being best for targeting hair follicles.
research A new model for cyclophosphamide-induced alopecia and its manipulation by cyclosporine a and topical dexamethasone
research 085 Coordinate expressions of cyclin-dependent kinase inhibitors and high sulfur protein in human hair follicles
research An Uncontrolled Innovative Test of Cryo-Chilled Carbon Dioxide as A Novel Amplification of a Nano-Botanical Multi-Acting Therapy in Advanced Stage Androgenetic Alopecia (Aga)
The treatment showed promising hair regrowth in advanced-stage hair loss.
research Oral Contraceptives and Cyproterone Acetate in Female Acne Treatment
Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.
research 856 Topical application of newly developed pseudoceramide improved both skin and hair barrier functions
Applying pseudoceramide improved skin and hair health.
research Placebo-controlled oral pulse prednisolone therapy in alopecia areata
Oral prednisolone helps hair regrowth in alopecia areata.
research Hair cortisol in polycystic ovary syndrome
Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.
research IN-SILICO STUDY OF BIOACTIVE COMPOUNDS OF NATURAL MATERIALS AS A JAK- SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION INHIBITOR FOR ANTI-ALOPECIA
Three compounds from Dadap leaves may help treat hair loss.
research [Differentiated application of oral contraceptives basing on the different side effects of synthetic progestins (author's transl)].
Choose oral contraceptives with specific side effects to manage issues like acne and avoid unwanted effects.