March 2024 in “Agriculture” CRISPR/Cas9 gene-editing shows promise for improving sheep and goat breeding but faces challenges with efficiency and accuracy.
September 2025 in “Animals” Key circRNAs play a role in wool follicle development, aiding in breeding better quality wool sheep.
16 citations
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September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
EDM is better for isolating and growing human foreskin fibroblasts, and PPP helps repair UVB damage.
75 citations
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March 1998 in “Journal of Investigative Dermatology” The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.
July 2007 in “Manuals in biomedical research” 21 citations
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October 2010 in “Encyclopedia of Life Sciences” Histocultures help personalize cancer treatments, study hair growth, and explore immune responses.
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June 2020 in “BMC genomics” A specific microRNA, chi-miR-30b-5p, slows down the growth of hair-related cells by affecting the CaMKIIδ gene in cashmere goats.
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December 1991 in “Annals of the New York Academy of Sciences” MYC protooncogenes may be important for hair growth, but more research is needed.
5 citations
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August 2021 in “Experimental dermatology” Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.
1 citations
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April 2019 in “Journal of Investigative Dermatology” VB1953 gel significantly reduced acne and resistant bacteria in patients who didn't respond to clindamycin.
July 2017 in “Cancer Research” Krt15+ cells in mice can resist radiation, regenerate tissue, and start tumors, suggesting new cancer treatment targets.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Folliculotropic mycosis fungoides has unique molecular features and cell interactions that could guide targeted therapy.
1 citations
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January 1971 in “Acta dermato-venereologica” Mice hair follicles take in the amino acid cystine.
64 citations
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February 2008 in “Cancer Research” Inactivating both p53 and Rb genes in mice speeds up aggressive skin cancer development.
March 2026 in “Materials Today Bio” The new cryo-MAP technique enables rapid and successful hair growth by transplanting hair follicle organoids.
10 citations
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January 1994 in “Advances in pharmacology” New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.
16 citations
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April 2000 in “Journal of Investigative Dermatology” The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
July 2025 in “Journal of Investigative Dermatology” Researchers created long-lasting, diverse skin organoids from mouse hair follicle stem cells, useful for studying skin.
66 citations
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October 2002 in “Human molecular genetics online/Human molecular genetics” A gene mutation in mice causes skin defects and early death.
January 2011 in “Junshi yixue” A mouse model for studying scleroderma in chronic graft-versus-host disease was successfully created.
November 1997 in “Open Archive (Karolinska Institutet)” PTCH gene mutations contribute to basal cell carcinoma development.
October 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Researchers developed a method to label and study human hair follicle stem cells using a fluorescent protein.
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October 1990 in “The Lancet” Some people have a genetic variation that makes them less effective at breaking down drugs.
January 2019 in “Institutional Repositories DataBase (IRDB)” Hair follicles and skin structures were successfully regenerated in the lab using specific cell arrangements and mechanical conditions.
73 citations
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August 2011 in “Stem Cell Research” Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.
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June 2016 in “Experimental Dermatology” MCHR2 gene duplications may be linked to alopecia areata.
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November 2022 in “Genetics selection evolution” Low-coverage sequencing is a cost-effective way to find genetic factors affecting rabbit wool traits.
12 citations
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January 2000 in “Biochemical and Biophysical Research Communications” The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.